Results 21 to 30 of about 188,322 (318)

Quercetin liposomes ameliorate streptozotocin-induced diabetic nephropathy in diabetic rats

open access: yesScientific Reports, 2020
The effects of quercetin liposomes (Q-PEGL) on streptozotocin (STZ)-induced diabetic nephropathy (DN) was investigated in rats. Male Sprague Dawley rats were used to establish a STZ induced DN model.
L. Tang   +6 more
semanticscholar   +1 more source

Peripheral Neuropathy Presents Similar Symptoms and Pathological Changes in Both High-Fat Diet and Pharmacologically Induced Pre- and Diabetic Mouse Models

open access: yesLife, 2021
The objective of the study was to compare the effects of experimentally induced type 1 or type 2 diabetes (T1D or T2D) on the functional, structural and biochemical properties of mouse peripheral nerves. Eight-week-old C57BL/6 mice were randomly assigned
Julia Jaroslawska   +7 more
doaj   +1 more source

Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review [PDF]

open access: yes, 2020
Background A growing number of epidemiological studies indicate that metabolic syndrome (MetS) and its associated features play a key role in the development of certain degenerative brain disorders, including Alzheimer’s disease and vascular dementia ...
Bell, J.D.   +9 more
core   +1 more source

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas.

open access: yesPhysiological Research, 2001
Alloxan and streptozotocin are widely used to induce experimental diabetes in animals. The mechanism of their action in B cells of the pancreas has been intensively investigated and now is quite well understood.
T. Szkudelski
semanticscholar   +1 more source

Prognosis of diabetes complications and efficacy of Guiera senegalensis aqueous leaf extract in streptozotocin induced-diabetic rats

open access: yesJournal of Applied Sciences and Environmental Management, 2018
Diabetes epidemics pose a serious health care problems and a huge burden on the economy of both developed and developing nations. Precise prognosis and the discovery of cost effective drugs for its management would serve as catalyst to economic recovery.
M Osibemhe, O.M. Bello, N Lawal
doaj   +1 more source

Effect of Hydroxytyrosol on Prdx6 Expression in Diabetic Rat Liver

open access: yesDüzce Tıp Fakültesi Dergisi, 2023
Aim: Oxidative stress caused by hyperglycemia, which is the most important complication of diabetes mellitus, causes liver damage. Hydroxytyrosol is a polyphenolic compound abundant in olive oil that protects the liver against oxidative damage ...
Eda Nur Almalı   +2 more
doaj   +1 more source

Effect of gestational diabetes on neuronal cells in rat cerebellum in early postnatal life [PDF]

open access: yes, 2014
Previous study has shown the adverse effects of gestational diabetes on hippocampal neuronal density in animal model. This study was conducted to determine the effect of gestational diabetes on rat cerebellum in early postnatal life. In this experimental
Ghafari, S.   +3 more
core   +1 more source

Enzymatic virgin coconut oil effect on urea and creatinine levels of hypercholesterolemia-diabetics induced Wistar male rats [PDF]

open access: yesPharmaciana
Coconut (Cocos nucifera L.) is an Indonesian commodity that has high economic value tall. Virgin Coconut Oil (VCO) is one of the processed coconut products whose selling value is very high, because the composition of VCO consists of medium-chain fatty ...
Niluh Puspita Dewi   +6 more
doaj   +1 more source

The Influence of Hyperactivity of the Hypothalamic-pituitary-adrenal Axis and Hyperglycemia on the 5-HT2A Receptor-mediated Wet-dog Shake Responses in Rats [PDF]

open access: yes, 2007
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis induces hyperglycemia and serotonin (5-HT)2A receptor supersensitivity. In the present study, to investigate the effect of hyperglycemia on the function of 5-HT2A receptors, we compared the 5-
Amano, Manabu   +7 more
core   +1 more source

Antidiabetic Effect of Standardized Chrysanthemum rubellum Hydroethanolic Extract by Targeting α-Glucosidase and the PTP-1B Signaling Pathway for Alleviating Diabetes in Experimental Model

open access: yesJournal of Pharmacopuncture, 2023
Objectives: The study's goal was to find out whether Chrysanthemum rubellum extract has anti-diabetic properties by concentrating on α-glucosidase and the PTP-1B signaling pathway. C. rubellum flowers were used for extraction using Methanol/water (80/20)
Bichitrananda Tripathy   +2 more
doaj   +1 more source

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