Results 51 to 60 of about 151,903 (303)

Antidiabetic activity of Coriandrum sativum in streptozotocin induced diabetic rats [PDF]

, 2019
Background: Diabetes mellitus (DM) can be defined as chronic hyperglycemia due to lack in insulin secretion and/or action. This study was designed to compare the antidiabetic activity of Coriandrum sativum L.
Raveendran, Siddhi, Rane, Pratik, Narkar, Nimish, Das, Sayan, Tilak, Abhijeet V., Chaware, Sanjeevani   +5 more
core   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats [PDF]

, 2004
Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats.BackgroundGlomerular and tubulointerstitial injury leads to chronic impairment of renal function, and thus, reversal of the injury may improve renal function and survival.
Fujisawa, Genro, Okada, Koji, Muto, Shigeaki, Kusano, Eiji, Fujita, Nobuya, Itabashi, Naoki, Ishibashi, Shun   +6 more
core   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

Antidiabetic and Synergistic Effects Study of Anthocyanin Fraction from Berberis integerrima Fruit on Streptozotocin-Induced Diabetic Rats Model [PDF]

Trends in Pharmaceutical Sciences, 2016
Introduction: Diabetes mellitus is a complex endocrine disorder. There is serious attempt to realize antidiabetic compound from natural sources to use with other drugs for reduction of diabetes complication.  Materials and Methods: Present study is based
Zahra Sabahi, Mohammad Javad Khoshnood-Mansoorkhani, Solmaz Rahmani Namadi, Mahmoodreza Moein   +3 more
doaj  

Constitutive nitric oxide synthase (cNOS) activity in Langerhans islets from streptozotocin diabetic rats

Brazilian Journal of Medical and Biological Research, 1998
Nitric oxide synthase activity was measured in Langerhans islets isolated from control and streptozotocin diabetic rats. The activity of the enzyme was linear up to 150 µg of protein from control rats and was optimal at 0.1 µM calcium, when it was ...
T.M. Fonovich de Schroeder, M.D. Carattino, M. Frontera, O.L. Catanzaro   +3 more
doaj   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

High-fat diet and streptozotocin in the induction of type 2 diabetes mellitus: a new proposal

Anais da Academia Brasileira de Ciências, 2019
Our objective was to establish a diabetes mellitus type 2 (DM2) model in rats using a high-fat diet and streptozotocin (HF-STZ). Male Wistar rats (240-250g) were divided into a control group (commercial feed), and HF-STZ group, (66.5%-commercial feed, 13.
DIEGO A. DE MAGALHÃES, WILLIAN T. KUME, FRANCYELE S. CORREIA, THAÍS S. QUEIROZ, EDGAR W. ALLEBRANDT NETO, MAÍSA P. DOS SANTOS, NAIR H. KAWASHITA, SUÉLEM A. DE FRANÇA   +7 more
doaj   +1 more source

Effect of sophora japonica total flavonoids on pancreas, kidney tissue morphology of streptozotocin-induced diabetic mice model

Saudi Journal of Biological Sciences, 2017
To observe effect of sophora japonica total flavonoids on pancreas, kidney tissue morphology of streptozotocin-induced diabetic mice model. Mice received tail vein injection of streptozotocin (60 mg/kg) for diabetes modeling.
Ting Wang, M. Miao, M. Bai, Yan Li, Min Li, Cai-Rong Li, Yu-Ying Xu   +6 more
semanticscholar   +1 more source

EFEK PEMBERIAN REBUSAN KULIT JENGKOL (ARCHIDENDRON PAUCIFLORUM) SEBAGAI ANTIDIABETIK TERHADAP KADAR MALONDIALDEHYDE (MDA) TIKUS PUTIH YANG DIINDUKSI STREPTOZOTOCIN

, 2020
Diabetes mellitus adalah gangguan metabolisme dengan banyak ragam gejala di mana peningkatan stres oksidatif memiliki peran penting dalam patogenesis penyakit dan dapat memicu terjadinya pembentukan spesies oksigen reaktif (ROS) sehingga meningkatkan ...

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