Results 51 to 60 of about 188,322 (318)

UHPLC/QTOF-MS-based metabolomics reveal the effect of Melastoma dodecandrum extract in type 2 diabetic rats

open access: yesPharmaceutical Biology, 2019
Context: Melastoma dodecandrum Lour. (Melastomataceae) is a traditional Chinese medicine. This is the first study to report a protective effect of the ethanol extract from M. dodecandrum (MDE) in type 2 diabetic (T2DM) rats. Objective: To investigate the
Jingyu Weng   +3 more
doaj   +1 more source

A Comprehensive Study of Chronic Diabetes Complications in Streptozotocin-Induced Diabetic Rat

open access: yesMakara Journal of Health Research, 2016
Background: The purpose of this study was to provide a reference of chronic diabetes complications by investigating the prolonged hyperglycemia effects on hematological, biochemical and histopathological changes (liver, kidney, spleen, cardiac muscle ...
Sinan MA Al-Mahmood   +5 more
doaj   +1 more source

Augmenter of liver regeneration enhances the success rate of fetal pancreas transplantation in rodents [PDF]

open access: yes, 1998
Background. Treatment of fetal pancreas (FP) isografts with insulin- like growth factor-I greatly improves the rate of conversion to euglycemia in diabetic rats.
Adams   +21 more
core   +1 more source

Thymoquinone Attenuates Cardiomyopathy in Streptozotocin-Treated Diabetic Rats

open access: yesOxidative Medicine and Cellular Longevity, 2018
Diabetic cardiomyopathy is a diabetic complication due to oxidative stress injuries. This study examined the protecting influence of thymoquinone (TQ) on diabetes-caused cardiac complications.
M. Atta   +5 more
semanticscholar   +1 more source

Quantitative studies of hepatocytes in periportal and perivenous zones of the liver lobules in diabetic rats [PDF]

open access: yes, 2007
This study was designed to evaluate the morphometric changes of parenchymal cells in the periportal (Z1) and perivenous (Z3) zones of the liver lobules that occur after Streptozotocin-induced diabetes in rats.
Ghafari, S., Golalipour, M.J.
core  

Self‐Powered Permeable Electronic Dressing for Exudate Management, Electrostimulation and Drug Delivery in Chronic Wound Healing

open access: yesAdvanced Functional Materials, EarlyView.
This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang   +12 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Effect of Phenolic and Alkaloid Extract of Senna Occidentalis Leaf on the Oxidative Status of the Heart in High Fat-Diet Streptozotocin-Induced Type 2 Diabetic Wistar Rats

open access: yesWorld Journal of Traditional Chinese Medicine
Objective: This research examined the effects of extracts (alkaloid and phenolic) from the leaves of Senna occidentalis on the oxidative status of heart in Wistar rats fed high-fat diets and induced with streptozotocin. Type 2 diabetes was established in
Emmanuel Saviour Saheed   +2 more
doaj   +1 more source

Protective effect of Urtica dioica L. (Urticaceae) on morphometric and morphologic alterations of seminiferous tubules in STZ diabetic rats [PDF]

open access: yes, 2011
Objective(s): Urtica dioica L. has been known as a medicinal plant in the world. This study was conducted to determine the effects of the hydroalcoholic extract of Urtica dioica leaves on seminiferous tubules of diabetic rats.
Azarhosh, R.   +4 more
core   +1 more source

Upregulation of inducible NO synthase by exogenous adenosine in vascular smooth muscle cells activated by inflammatory stimuli in experimental diabetes [PDF]

open access: yes, 2016
BACKGROUND: Adenosine has been shown to induce nitric oxide (NO) production via inducible NO synthase (iNOS) activation in vascular smooth muscle cells (VSMCs). Although this is interpreted as a beneficial vasodilating pathway in vaso-occlusive disorders,
Cignarella, Andrea   +4 more
core   +2 more sources

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