Chemical composition, in vitro biological activity and in silico molecular docking of fixed oil of Linum strictum. ABSTRACT The present study investigated the fatty acid composition of Linum strictum seed oil and evaluated its antibacterial, antibiofilm, anticoagulant, and α‐amylase inhibitory activities.
Hayet Edziri +8 more
wiley +1 more source
Comment on Sklifasovskaya et al. Hypertension and Diabetes Cooperatively Drive HSP90 Activation, HSP70 Suppression, and Left Ventricular Interstitial Expansion: Relevance to Maladaptive Myocardial Remodeling. <i>Pathophysiology</i> 2026, <i>33</i>, 19. [PDF]
Amaç B.
europepmc +1 more source
USP18 Serves as a Key Mediator of cGAS‐STING for Cardiac Aging in Diabetes
ABSTRACT Diabetes accelerates cardiac aging, but the molecular mechanisms that link metabolic stress to myocardial senescence remain insufficiently defined. This study investigated factors driving diabetes‐associated cardiac aging with a focus on the role of USP18.
Xunxi Deng +6 more
wiley +1 more source
cGAS-STING Pathway Mediates Retinal Pigmental Epithelial Dysfunction in Diabetic Retinopathy. [PDF]
Zhu Z +7 more
europepmc +1 more source
FOXO6 suppresses the transcriptional expression of SMURF2, thereby limiting the ubiquitination and degradation of NR4A1. Stabilized NR4A1 promotes ferroptosis in RPE cells, contributing to the progression of diabetic retinopathy. Abstract Diabetic retinopathy (DR) is the main cause of vision loss, with retinal pigment epithelial (RPE) cell dysfunction ...
Qiao Chen +4 more
wiley +1 more source
Aqueous <i>Artemisia herba-alba</i> Asso Preparation as a Botanical Adjunct to Dapagliflozin: Enhanced Glycemic Control in Streptozotocin-Induced Diabetic Rats. [PDF]
Hailat MM +10 more
europepmc +1 more source
Polyphenol assembly chemistry provides a versatile basis for antibacterial biomaterials. Matching material format and function to the distinct barriers of wound, respiratory, intestinal, and implant‐associated infections is central to effective and translatable design. ABSTRACT Bacterial infections involving multidrug‐resistant pathogens and persistent
Wei Yang +4 more
wiley +1 more source
NSUN4‐mediated upregulation of SMURF1 promoted mitochondrial fission and inhibited mitochondrial fusion to accelerate DN progression via increasing CAMK1 ubiquitination. Abstract Background NOP2/Sun RNA methyltransferase family member 4 (NSUN4)‐mediated 5‐methylcytosine (m5C) modification has been implicated in diabetes‐related diseases.
Danyi Yang +5 more
wiley +1 more source
Angiotensin receptor blocker ameliorates the development of tubulointerstitial injury and fibrosis associated with tubular proteinuria observed in subclinical diabetic kidney disease. [PDF]
Campos MR +9 more
europepmc +1 more source
HAR may improve T2DM by enhancing antioxidant defences through Nrf2 activation while suppressing inflammation and RAS activity, supporting its capability to treat diabetes. ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation.
Farima Malekinia +5 more
wiley +1 more source

