Results 231 to 240 of about 151,903 (303)

Fatty Acid Composition of Fixed Oil of Linum strictum and Its Antibiofilm, Anticoagulant, and α‐Amylase Inhibitory Effects–In Vitro and In Silico Study

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Chemical composition, in vitro biological activity and in silico molecular docking of fixed oil of Linum strictum. ABSTRACT The present study investigated the fatty acid composition of Linum strictum seed oil and evaluated its antibacterial, antibiofilm, anticoagulant, and α‐amylase inhibitory activities.
Hayet Edziri   +8 more
wiley   +1 more source

USP18 Serves as a Key Mediator of cGAS‐STING for Cardiac Aging in Diabetes

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Diabetes accelerates cardiac aging, but the molecular mechanisms that link metabolic stress to myocardial senescence remain insufficiently defined. This study investigated factors driving diabetes‐associated cardiac aging with a focus on the role of USP18.
Xunxi Deng   +6 more
wiley   +1 more source

FOXO6 inhibits SMURF2‐mediated ubiquitination and degradation of NR4A1 to promote retinal pigment epithelial cell ferroptosis in diabetic retinopathy

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
FOXO6 suppresses the transcriptional expression of SMURF2, thereby limiting the ubiquitination and degradation of NR4A1. Stabilized NR4A1 promotes ferroptosis in RPE cells, contributing to the progression of diabetic retinopathy. Abstract Diabetic retinopathy (DR) is the main cause of vision loss, with retinal pigment epithelial (RPE) cell dysfunction ...
Qiao Chen   +4 more
wiley   +1 more source

Aqueous <i>Artemisia herba-alba</i> Asso Preparation as a Botanical Adjunct to Dapagliflozin: Enhanced Glycemic Control in Streptozotocin-Induced Diabetic Rats. [PDF]

open access: yesPharmaceutics
Hailat MM   +10 more
europepmc   +1 more source

Polyphenol‐Based Biomaterials for Antibacterial Infection Management: From Assembly Chemistry to Infection Site‐Specific Therapeutic Platforms

open access: yescMat, Volume 3, Issue 3, September 2026.
Polyphenol assembly chemistry provides a versatile basis for antibacterial biomaterials. Matching material format and function to the distinct barriers of wound, respiratory, intestinal, and implant‐associated infections is central to effective and translatable design. ABSTRACT Bacterial infections involving multidrug‐resistant pathogens and persistent
Wei Yang   +4 more
wiley   +1 more source

NSUN4‐dependent m5C modification facilitates mitochondrial fission to accelerate diabetic nephropathy process via regulating SMURF1/CAMK1 axis

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
NSUN4‐mediated upregulation of SMURF1 promoted mitochondrial fission and inhibited mitochondrial fusion to accelerate DN progression via increasing CAMK1 ubiquitination. Abstract Background NOP2/Sun RNA methyltransferase family member 4 (NSUN4)‐mediated 5‐methylcytosine (m5C) modification has been implicated in diabetes‐related diseases.
Danyi Yang   +5 more
wiley   +1 more source

Angiotensin receptor blocker ameliorates the development of tubulointerstitial injury and fibrosis associated with tubular proteinuria observed in subclinical diabetic kidney disease. [PDF]

open access: yesFront Pharmacol
Campos MR   +9 more
europepmc   +1 more source

Potential Involvement of Redox and Inflammatory Signalling in the Antihyperglycemic and Antioxidant Effects of Harmaline in Male Mice With Type 2 Diabetes

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
HAR may improve T2DM by enhancing antioxidant defences through Nrf2 activation while suppressing inflammation and RAS activity, supporting its capability to treat diabetes. ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation.
Farima Malekinia   +5 more
wiley   +1 more source

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