Results 251 to 260 of about 151,903 (303)

Exercise intensity-dependent metabolic adaptations in streptozotocin-induced diabetic rats: modulatory effects of apple cider vinegar on inflammatory and endocrine biomarkers. [PDF]

Front Physiol
Akay MK, Pancar Z, Darendeli MK, Ulema MS, Karaca B, Ulusal H, Bozkurt AS, Taşdoğan AM, Yan X.   +8 more
europepmc   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

Comparative Evaluation of the Antihyperglycemic Potential of <i>Coccinia cordifolia</i> and <i>Gynura procumbens</i> Leaf Extracts: Integrated Phytochemical, In Vivo, Molecular Docking, and DFT Investigations. [PDF]

Food Sci Nutr
Morshed AJM, Das SK, Islam Z, Akter M, Bakar MA, Mostafa M, Akter R, Sharmin T, Uddin MH.   +8 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis. [PDF]

Mol Med Rep
Chen J, Zhang W, Hong T, Wang J, Chen C, Zhang Y, Hu M, You N, Huang J.   +8 more
europepmc   +1 more source

Icariside II in Neurological Disorders: Mechanistic Insights Into Alzheimer's Disease, Cerebral Ischemia and Parkinson's Disease

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The graphical abstract represents the underlying neuroprotective potential of ICS II against Alzheimer's disease, Cerebral ischemia and Parkinson disease. ICS II downregulates ROS production, inflammation, mitochondrial dysfunction and apoptosis along with regulating their key signalling pathways.
Ashutosh Solanki, Khushi Sharma, Jagrati Jain, Niraj Kumar Singh, Praveen T. Krishnamurthy   +4 more
wiley   +1 more source

Correction: Alhamhoom et al. Synergistic Antihyperglycemic and Antihyperlipidemic Effect of Polyherbal and Allopolyherbal Formulation. <i>Pharmaceuticals</i> 2023, <i>16</i>, 1368. [PDF]

Pharmaceuticals (Basel)
Alhamhoom Y, Ahmed SS, M RK, Salahuddin MD, R BD, Ahmed MM, Farhana SA, Rahamathulla M.   +7 more
europepmc   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

Effects of coenzyme Q10 on retinal inflammation in streptozotocin-induced diabetic rats. [PDF]

BMC Ophthalmol
Akdoğan M, Karaca Ç, Demirel HH.
europepmc   +1 more source

S100A8 Mediating TLR4/NF‐κB Axis Activation to Inhibit Diabetic Foot Healing in Bacterial Colonization

The Journal of Gene Medicine, Volume 28, Issue 9, September 2026.
In a hyperglycemic and inflammatory microenvironment, keratinocytes and macrophages upregulate S100A8. This activates the TLR4/NF‐κB pathway, leading to increased pro‐inflammatory cytokines (IL‐1β, TNF‐α, and IL‐6), reduced antimicrobial peptides (AMPs), impaired keratinocyte migration/proliferation, and enhanced S.
Qi Wang, Tong Sun, YanFei Xu, Li Zhang, Jiao Li, Lei Guo   +5 more
wiley   +1 more source