Results 261 to 270 of about 188,322 (318)
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Hyperlipoproteinemia in Streptozotocin-treated Rats
Diabetes, 1976In order to study hyperlipidemia in diabetes mellitus, rats were made diabetic by administration of streptozotocin and the optimal conditions for production of severe and persistent hyperlipoprotenemia determined. Two groups of rats were compared: rats fed sucrose-rich diets and rats fed laboratory chow.
H, Bar-On, P S, Roheim, H A, Eder
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Hypercalcemia and Streptozotocin
Annals of Internal Medicine, 1974Excerpt To the editor: I read with interest the article, "Islet Cell Tumors: Current Concepts and Management," by Schein and associates (Ann Intern Med79:239-257, 1973).
ERIC A. LARYEA +2 more
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Early streptozotocin diabetes and hunger
Physiology & Behavior, 1983The initial effect of streptozotocin diabetes is not hyperphagia, but reduced food intake. Diabetic hyperphagia reaches maximum only after many days. Utilization of body fat may account for the delayed appearance of diabetic hyperphagia; this effect may be mediated by plasma fat metabolites.
R G, Carpenter, S P, Grossman
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Streptozotocin treatment for malignant insulinoma
Irish Journal of Medical Science, 1974A CASE of malignant insulinoma was treated with streptozotocin intravenously and by coeliac axis infusion. Treatment was repeated over a period of two years, and the total dose was 82.5g. Several clinical remissions of hypoglycaemia were obtained despite the persistence of abnormally elevated plasma insulin levels.
J, O'Donnell +4 more
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Streptozotocin for metastatic malignant melanoma
American Journal of Clinical Oncology, 1985Streptozotocin was administered at a dose of 500 mg/m2/day by continuous infusion for 120 hours to 14 patients with advanced malignant melanoma. No responses were observed in this group of patients and the median survival for the entire group was 2 months. At the dose and schedule delivered, streptozotocin is inactive against malignant melanoma.
J J, Lokich +4 more
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Metastatic Insulinoma Treated with Streptozotocin
Annals of Internal Medicine, 1971Abstract A patient with hepatic metastases of an insulin-producing islet cell carcinoma has been successfully treated with streptozotocin.
P H, Schreibman +2 more
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Diabetogenic action of streptozotocin
Trends in Pharmacological Sciences, 1982Abstract Streptozotocin (SZ) possesses four distinct biological activities: antibiotic, antitumoral, cancer producing and diabetogenic. SZ is a highly effective cytotoxic agent for pancreatic β cells; the possible reason for high specificity of SZ towards the pancreatic β cells may be a high capacity of these cells to accumulate the substance.
L.M. Srivastava, P.S. Bora, S.D. Bhatt
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ChemInform Abstract: STREPTOZOTOCIN
Chemischer Informationsdienst, 1972AbstractIn einer umfangreichen Zusammenfassung mit 236 Literaturzitaten wird die Gewinnung des Streptozotocins (I), seine Struktur und Synthese, seine antifbiotische Wirksamkeit, cxtostatische, carcinogene und mutagene Wirkung, der Stoffwechsel und die Toxizität des Streptozotocins erörtert.
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