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Mechanisms of stress (Takotsubo) cardiomyopathy
Nature Reviews Cardiology, 2010Stress cardiomyopathy, also referred to as Takotsubo cardiomyopathy, transient apical ballooning or broken heart syndrome, is a disorder associated with transient left ventricular dysfunction. Symptoms include acute chest pain and dyspnea accompanied by electrocardiographic changes, such as ST-segment elevation and T-wave inversions, minimal elevation ...
Holger M, Nef +3 more
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Mechanics of Elastic Stress Transfer
2016At the beginning of the loading regime—when the DFRC is subjected to low applied loads—the response of the DFRC to the applied load is regulated by the elastic stress transfer mechanism. As the load increases, eventually the DFRC undergoes a transition from the elastic stress transfer stage to the plastic stress transfer stage.
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Cell adhesion mechanisms and stress relaxation in the mechanics of tumours
Biomechanics and Modeling in Mechanobiology, 2008Tumour cells usually live in an environment formed by other host cells, extra-cellular matrix and extra-cellular liquid. Cells duplicate, reorganise and deform while binding each other due to adhesion molecules exerting forces of measurable strength. In this paper, a macroscopic mechanical model of solid tumour is investigated which takes such adhesion
D. AMBROSI, PREZIOSI, LUIGI
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Effects of stress on muscarinic mechanisms
Neuroscience & Biobehavioral Reviews, 1988Hyperactivity of muscarinic mechanisms may be involved in the patho-physiology of depressive disorders and stress. The literature emphasizes the impact of stress on aminergic networks and muscarinic mechanisms are generally not accorded a significant role in the neurobiology of stress.
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Oxidative stress as a mechanism of teratogenesis
Birth Defects Research Part C: Embryo Today: Reviews, 2006Emerging evidence shows that redox-sensitive signal transduction pathways are critical for developmental processes, including proliferation, differentiation, and apoptosis. As a consequence, teratogens that induce oxidative stress (OS) may induce teratogenesis via the misregulation of these same pathways.
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Learning to cope with stress: psychobiological mechanisms of stress resilience
Reviews in the Neurosciences, 2012Stress is the main non-genetic source of psychopathology. Therefore, the identification of neurobiological bases of resilience, the resistance to pathological outcomes of stress, is a most relevant topic of research. It is an accepted view that resilient individuals are those who do not develop helplessness, or other depression-like phenotypes ...
CABIB, Simona +2 more
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Signal Transduction and Mechanical Stress
Science's STKE, 2004Bone undergoes a constant process of remodeling in which mass is retained or lost in response to the relative activity of osteoblasts and osteoclasts. Weight-bearing exercise—which is critical for retaining skeletal integrity—promotes osteoblast function, whereas a lack of mechanical stimulation, as seen during spaceflight or prolonged bed rest, can ...
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The Molecular Mechanism of Macrophages in Response to Mechanical Stress
Annals of Biomedical EngineeringMacrophages, a type of functionally diversified immune cell involved in the progression of many physiologies and pathologies, could be mechanically activated. The physical properties of biomaterials including stiffness and topography have been recognized as exerting a considerable influence on macrophage behaviors, such as adhesion, migration ...
Yuntong, Su, Xing, Yin
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The Virial Stress Is Not a Measure of Mechanical Stress
MRS Proceedings, 2002AbstractThe virial stress is the most commonly used definition of stress in discrete molecular systems. This stress includes two parts. The first part depends on the mass and velocity of atomic particles, reflecting an assertion that mass transfer causes mechanical stress to be applied on stationary spatial surfaces external to an atomic particle ...
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