Results 31 to 40 of about 956,391 (287)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Study on coal crack propagation and failure mode with different moisture content under uniaxial compression

open access: yesGong-kuang zidonghua, 2022
In order to study the influence of moisture intrusion on crack propagation and failure mode of loaded coal, uniaxial compression tests and acoustic emission monitoring of coal with different moisture contents are carried out.
LU Weiyong   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Abstract 008 | Functional and structural specialization of human donor tendons

open access: yesEuropean Journal of Translational Myology
Consideration of the physiological properties of skeletal muscles in upper extremity surgery is appropriate since it is important to match donor and acceptor muscle functional properties.
Jan Fridén
doaj   +1 more source

Modeling of mechanical behavior of cork in compression

open access: yesFracture and Structural Integrity, 2020
The present work consists of a contribution in modeling the mechanical behavior of cork in compression. For this purpose, compression tests are performed in the non-radial direction on high density reproduction cork samples.
Youns Saadallah
doaj   +1 more source

Thermal Fluctuations and Rubber Elasticity

open access: yes, 2006
The effects of thermal elastic fluctuations in rubber materials are examined. It is shown that, due to an interplay with the incompressibility constraint, these fluctuations qualitatively modify the large-deformation stress-strain relation, compared to ...
L. R. G. Treloar   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Evaluasi Tegangan-Regangan Dengan Pemodelan Silinder Beton

open access: yesRekayasa Sipil, 2018
Compressive strength is one of the main parameters in the analysis of concrete behavior. In general, the compressive strength of the concrete will be tested in the laboratory using the Uniaxial Compression Test tool.
Ming Narto Wijaya
doaj   +1 more source

Mechanical properties of flax short fiber reinforced silicone rubber composites

open access: yesXi'an Gongcheng Daxue xuebao, 2023
In order to improve the mechanical properties of short flax fiber reinforced silicone rubber composites, flax short fiber/silicone rubber composite was prepared with flax short fiber as reinforcement and silicone rubber as matrix.
ZHOU Zixiang, CHEN Si
doaj   +1 more source

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