Results 41 to 50 of about 4,438,120 (290)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Modeling of mechanical behavior of cork in compression
Fracture and Structural Integrity, 2020 The present work consists of a contribution in modeling the mechanical behavior of cork in compression. For this purpose, compression tests are performed in the non-radial direction on high density reproduction cork samples.
Youns Saadallah
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Mechanical properties of flax short fiber reinforced silicone rubber composites
Xi'an Gongcheng Daxue xuebao, 2023 In order to improve the mechanical properties of short flax fiber reinforced silicone rubber composites, flax short fiber/silicone rubber composite was prepared with flax short fiber as reinforcement and silicone rubber as matrix.
ZHOU Zixiang, CHEN Si
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Comparative Finite Element Analysis of Exoskeletons Materials for Durability in Rehabilitation
Recoletos Multidisciplinary Research JournalBackground: Assistive devices, such as exoskeletons, are one of the biggest breakthroughs in the medical industry, especially regarding physical therapy and rehabilitation. However, many of these devices are expensive.
Michael Leander Roque +4 more
doaj +1 more source
Evaluasi Tegangan-Regangan Dengan Pemodelan Silinder Beton
Rekayasa Sipil, 2018 Compressive strength is one of the main parameters in the analysis of concrete behavior. In general, the compressive strength of the concrete will be tested in the laboratory using the Uniaxial Compression Test tool.
Ming Narto Wijaya
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source