Results 61 to 70 of about 970,478 (306)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Simulation analysis of stress-strain performance for a lightweight X-ray pulsar detection telescope frame structure

Frontiers in Astronomy and Space Sciences
With the continuous deepening of human exploration of the universe, space telescopes have emerged as pivotal tools for obtaining information about celestial bodies and their evolutionary principles.
Qingyong Zhou, Qingyong Zhou, Zhiqiang Huang, Bin Xu, Yaohu Lei, Jianguo Lei, Hang Zhao, Chaojing Ye, Likuan Zhu   +8 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Structural Performance of uPVC Confined Concrete Equivalent Cylinders Under Axial Compression Loads

Buildings, 2019
There is always a need for more durable, ductile, and robust materials for buildings, bridges, and other infrastructure due to the drawbacks of existing construction materials.
Abraham Mengesha Woldemariam, Walter O. Oyawa, Timothy Nyomboi   +2 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Influence of ultrasonic vibration on tensile properties and dislocation distribution of titanium foil

Cailiao gongcheng, 2019
The plastic deformation with respect to dislocation distribution of titanium foil under ultrasonic vibration was studied. The influencing rule of different ultrasonic vibration modes on the stress-strain,elongation and dislocation distribution of ...
JIANG Shao-song, YANG Tian-hao, SUN Hong-yu, HE Yu-shi, LU Zhen, WANG Rui-zhuo   +5 more
doaj   +1 more source

Structural behavior of tapered inflated fabric cylinders under various loading conditions [PDF]

, 1971
Method analyzes inflatable structures and considers axial loads, torsional moment, and internal pressure. Behavior depends on anistropic nature and large deflection stress-strain characteristics of fabric material.
Kovalevsky, L., Risk, F. L.
core   +1 more source

A study of the static yield stress in a binary Lennard-Jones glass

, 2003
The stress-strain relations and the yield behavior of model glass (a 80:20 binary Lennard-Jones mixture) is studied by means of MD simulations. First, a thorough analysis of the static yield stress is presented via simulations under imposed stress ...
Berthier L., Bonn D., Chen L. J., Coussot P., Coussot P., Da Cruz F., David Lu C.-Y., Debrégeas G., F. Varnik, He G., Ho Huu C., J.-L. Barrat, L. Bocquet, Picard G., Pignon F., Rottler Jörg, van Aken B., Walls H. J.   +17 more
core   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Molecular Dynamics Simulation of the Dynamic Mechanical Behavior of FeNiCrMn High-Entropy Alloy

Nanomaterials
High-entropy alloys (HEAs) exhibit excellent properties such as high strength, good ductility, superior corrosion resistance, and thermal stability, making them highly promising for applications in the aerospace, energy, and automotive industries.
Haorui Liu, Nana Yang, Shu Xiao, Hu Zhang, Sheng Zhao, Kai Ma, Ning Mi   +6 more
doaj   +1 more source