Results 41 to 50 of about 956,391 (287)

Experimental Verification of the Number Relation at Room and Elevated Temperatures [PDF]

open access: yes, 1983
The accuracy of the Neuber equation for predicting notch root stress-strain behavior at room temperature and at 650 C was experimentally investigated.
Lucas, L. J., Martin, J. F.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Comparative Finite Element Analysis of Exoskeletons Materials for Durability in Rehabilitation

open access: yesRecoletos Multidisciplinary Research Journal
Background: Assistive devices, such as exoskeletons, are one of the biggest breakthroughs in the medical industry, especially regarding physical therapy and rehabilitation. However, many of these devices are expensive.
Michael Leander Roque   +4 more
doaj   +1 more source

Behavior of large-scale rectangular columns confined with FRP composites [PDF]

open access: yes, 2010
This paper focuses on axially loaded, large-scale rectangular RC columns confined with fiber-reinforced polymer (FRP) wrapping. Experimental tests are conducted to obtain the stress-strain response and ultimate load for three field-size columns having ...
Toutanji, H   +3 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Stress-strain characteristic of SFRC using recycled fibres

open access: yes, 2006
This paper presents work from a comprehensive study on the development of a flexural design framework for concrete reinforced with steel fibres that are recovered from used tyres.
Neocleous, K.   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Microscopic origin of nonlinear non-affine deformation and stress overshoot in bulk metallic glasses [PDF]

open access: yes, 2014
The atomic theory of elasticity of amorphous solids, based on the nonaffine response formalism, is extended into the nonlinear stress-strain regime by coupling with the underlying irreversible many-body dynamics.
Schall, P.   +2 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

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