Results 111 to 120 of about 10,727,912 (338)

Psychologists’ involvement in and experiences of treating patients with stress-related exhaustion in primary care

open access: yesBMC Primary Care
Background Primary health care is the setting for most patients with stress-related mental health problems. Good care processes are important for patients with stress-related mental health problems and the complex needs of these patients has become a ...
Susanne Ellbin   +3 more
doaj   +1 more source

The Effects of Physical Activity on Stress-induced Cardiac Fibrosis [PDF]

open access: yes, 2017
Purpose: This study examined whether routine physical activity limits stress-induced tissue remodeling processes that lead to cardiac fibrosis. The study also explored whether the cardiac urocortin 2/corticotropin releasing factor receptor 2β pathway was
Coste, Sarah C., Kinney, Erin M.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

‘My child could have died’: counterfactual thoughts and psychological distress in parents of trauma survivors

open access: yesEuropean Journal of Psychotraumatology
Background: After exposure to a potentially traumatic event, survivors may experience thoughts about ‘what could have happened’, referred to as counterfactual thoughts (CFTs).
Ines Blix   +6 more
doaj   +1 more source

The Effect of Chronic Stress on Generalization of Conditioned Fear [PDF]

open access: yes, 2016
Prior lifetime experience of stress is a significant risk factor for posttraumatic stress disorder (PTSD) and other anxiety disorders. The mechanisms by which stress conveys these effects are unknown and likely involve complicated neurobiological ...
Senatore, Amanda J
core   +1 more source

Stress [PDF]

open access: yesCurrent Biology, 2011
Procko, Carl, Shaham, Shai
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress [PDF]

open access: bronze, 2012
Alberto Ciccia   +12 more
openalex   +1 more source

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