Results 51 to 60 of about 3,798,231 (274)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Effects of external mechanical loading on stress generation during lithiation in Li-ion battery electrodes [PDF]

Electrochimica Acta, 185, 28-33 (2015), 2019
Li-ion batteries are ineluctably subjected to external mechanical loading or stress gradient. Such stress can be induced in battery electrode during fabrication and under normal operation. In this paper, we develop a model for stresses generated during lithiation in the thin plate electrode considering the effects of external mechanical loading.
arxiv   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Significance of dietary quinoa husk (Chenopodium quinoa) in gene regulation for stress mitigation in fish

Scientific Reports
The persistent challenges posed by pollution and climate change are significant factors disrupting ecosystems, particularly aquatic environments. Numerous contaminants found in aquatic systems, such as ammonia and metal toxicity, play a crucial role in ...
Neeraj Kumar, Supriya Tukaram Thorat, Aliza Pradhan, Jagadish Rane, Kotha Sammi Reddy   +4 more
doaj   +1 more source

Cooler canopy leverages sorghum adaptation to drought and heat stress

Scientific Reports, 2022
In the present study, individual and combined effects of drought and heat stress were investigated on key physiological parameters (canopy temperature, membrane stability index, chlorophyll content, relative water content, and chlorophyll fluorescence ...
Aliza Pradhan, Lalitkumar Aher, Vinay Hegde, Krishna Kumar Jangid, Jagadish Rane   +4 more
doaj   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Effects of procedural justice on prospective antidepressant medication prescription: a longitudinal study on Swedish workers

BMC Public Health, 2020
Background Procedural justice has been linked to several mental health problems, but most studies have used self-reported data. There exist a need to assess the link between procedural justice and health using outcomes that are not only self-reported ...
Viktor Persson, Constanze Eib, Claudia Bernhard-Oettel, Constanze Leineweber   +3 more
doaj   +1 more source