Results 71 to 80 of about 3,798,231 (274)

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Root growth, yield and stress tolerance of soybean to transient waterlogging under different climatic regimes

Scientific Reports
Global warming-induced abiotic stresses, such as waterlogging, significantly threaten crop yields. Increased rainfall intensity in recent years has exacerbated waterlogging severity, especially in lowlands and heavy soils.
Vinay M. Gangana Gowdra, B. S. Lalitha, Hanamant M. Halli, E. Senthamil, Priyanka Negi, H. M. Jayadeva, P. S. Basavaraj, C. B. Harisha, K. M. Boraiah, Sandeep B. Adavi, P. G. Suresha, Raghavendra Nargund, Ganesh Mohite, K. Sammi Reddy   +13 more
doaj   +1 more source

Impact of mono- and di-β-galactose moieties in in vitro / in vivo anticancer efficacy of pyropheophorbide-carbohydrate conjugates by photodynamic therapy

European Journal of Medicinal Chemistry Reports, 2022
To investigate the impact of mono- and di-β-galactose moieties in tumor uptake and photodynamic therapy (PDT) efficacy, HPPH [3-(1′-hexyloxy)ethyl-3-devinylpyropheophorobide-a], the meso pyropheophorbide-a [3-ethyl-3-devinyl-pyropheophorbide-a], and the ...
Mykhaylo Dukh, Joseph Cacaccio, Farukh A. Durrani, Ishaan Kumar, Ramona Watson, Walter A. Tabaczynski, Penny Joshi, Joseph R. Missert, Heinz Baumann, Ravindra K. Pandey   +9 more
doaj  

Burnout and hypocortisolism – a matter of severity? A study on ACTH and cortisol responses to acute psychosocial stress

Frontiers in Psychiatry, 2015
Background: Common consequences of long-term psychosocial stress are fatigue and burnout. It has been suggested that burnout could be associated with hypocortisolism, thus, inability to produce sufficient amounts of cortisol.
Anna-Karin eLennartsson, Anna eSjörs, Thomas eLjung, Peter eWährborg, Ingibjörg eJonsdottir, Ingibjörg eJonsdottir   +5 more
doaj   +1 more source

A new approach for the inversion of residual stress based on acoustoelasticity theory and full waveform inversion [PDF]

Mechanics Research Communications, Volume 145, 2025
Acoustoelasticity theory has been widely used to evaluate the residual stress (or prestress), almost all the available ultrasonic stress detection methods are based on the relationship between the magnitude of stress and wave speed, but these measurement methods make the assumption that the stress is uniform, only one point or average stress in the ...
arxiv   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Health care needs, experiences, and satisfaction after terrorism: a longitudinal study of parents of survivors of the Utøya attack

BMC Health Services Research
Background There is scarce knowledge on the health care follow-up of parents of terror attack survivors. This study focused on the mothers and fathers of survivors and examined (1) their perceived health care needs relative to their psychological ...
Ida Frugård Strøm, Tore Wentzel-Larsen, Synne Stensland, Grete Dyb, Lise Eilin Stene   +4 more
doaj   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Generalized Stress Concentration Factors for Equilibrated Forces and Stresses [PDF]

arXiv, 2004
As a sequel to a recent work we consider the generalized stress concentration factor, a purely geometric property of a body that for the various external loading fields indicates the worst ratio between the maximum of the optimal stress and maximum of the external loading.
arxiv