Results 261 to 270 of about 11,866,665 (347)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
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Optimal design of functionally graded material for stress concentration reduction
Structures, 2021Young’s modulus distribution, a significant parameter of a functionally graded material, is investigated to reduce the stress concentration. An evolutionary optimization algorithm of Young’s modulus is developed.
Yicong Zhou, Qiyin Lin, Jun Hong
exaly +2 more sources
Construction and Building Materials, 2020
In order to investigate the influence of characteristic parameters of pits on the strength and stress concentration factor of cable steel wire, 198 cable steel wires with pits were manually prepared. The variation law of stress distribution of steel wire
Rou Li, Changqing Miao
exaly +2 more sources
In order to investigate the influence of characteristic parameters of pits on the strength and stress concentration factor of cable steel wire, 198 cable steel wires with pits were manually prepared. The variation law of stress distribution of steel wire
Rou Li, Changqing Miao
exaly +2 more sources
ACS Nano, 2023
Nickel-rich LiNi0.8Co0.15Al0.015O2 (NCA) with excellent energy density is considered one of the most promising cathodes for lithium-ion batteries.
Yu Zhou +14 more
semanticscholar +1 more source
Nickel-rich LiNi0.8Co0.15Al0.015O2 (NCA) with excellent energy density is considered one of the most promising cathodes for lithium-ion batteries.
Yu Zhou +14 more
semanticscholar +1 more source
Acta Biomaterialia, 2023
It is well documented that overly stiff skeletal replacement and fixation devices may fail and require revision surgery. Recent attempts to better support healing and sustain healed bone have looked at stiffness-matching of these devices to the desired ...
Agnieszka Chmielewska, David Dean
semanticscholar +1 more source
It is well documented that overly stiff skeletal replacement and fixation devices may fail and require revision surgery. Recent attempts to better support healing and sustain healed bone have looked at stiffness-matching of these devices to the desired ...
Agnieszka Chmielewska, David Dean
semanticscholar +1 more source
, 2021
A sudden change in the geometrical parameters of a material, such as bends, T-branches, and welded joints may increase the stress concentration, which in turn may enhance the diffusible hydrogen concentration.
T. Nguyen +4 more
semanticscholar +1 more source
A sudden change in the geometrical parameters of a material, such as bends, T-branches, and welded joints may increase the stress concentration, which in turn may enhance the diffusible hydrogen concentration.
T. Nguyen +4 more
semanticscholar +1 more source
, 2021
Nowadays automated welding processes produce high-quality welds with smooth and regular global weld geometry. However, the local geometry of the weld exhibits a certain amount of variance in its topography due to dynamic effects of the welding process ...
Markus Ottersböck +2 more
semanticscholar +1 more source
Nowadays automated welding processes produce high-quality welds with smooth and regular global weld geometry. However, the local geometry of the weld exhibits a certain amount of variance in its topography due to dynamic effects of the welding process ...
Markus Ottersböck +2 more
semanticscholar +1 more source
Influence of weld geometry on stress concentration factor distributions in tubular joints
, 2021Fatigue design of welded tubular joints relies on an extensive number of parametric equations that allow calculation of the stress concentration factors at characteristic locations around the weld circumference. These equations were developed with finite
K. Hectors, Wim De Waele
semanticscholar +1 more source
Peterson's Stress Concentration Factors
, 2020Index to the Stress Concentration Factors. Preface for the Third Edition. Preface for the Second Edition. 1. Definitions and Design Relations. 1.1 Notation. 1.2 Stress Concentration. 1.3 Stress Concentration as a Two-Dimensional Problem.
W. Pilkey
semanticscholar +1 more source