Results 221 to 230 of about 2,700,982 (237)

Muscle iron in stress erythropoiesis?

Blood, 2009
Two related recent studies on erythropoiesis by Robach and colleagues describe surprising differential responses to erythropoietin with respect to skeletal muscle iron mobilization, apparently depending on normoxic versus hypoxic conditions.
Marc, Kerenyi, Ernst W, Müllner
openaire   +2 more sources

LYL-1 deficiency induces a stress erythropoiesis

Experimental Hematology, 2011
LYL-1 is a transcription factor containing a basic helix-loop-helix motif closely related to SCL/TAL-1, a regulator of erythroid differentiation. Because LYL-1 is expressed in erythroid cell populations, we addressed its role in erythropoiesis using knockin mice.Erythropoiesis of LYL-1(-/-) mice was studied by progenitor assays, flow cytometry ...
Claude, Capron, Catherine, Lacout, Yann, Lécluse, Orianne, Wagner-Ballon, Anna-Lila, Kaushik, Elisabeth, Cramer-Bordé, Fred, Sablitzky, Dominique, Duménil, William, Vainchenker   +8 more
openaire   +2 more sources

Erythropoiesis-stimulating agent withdrawal and oxidative stress in hemodialysis [PDF]

Clinical Nephrology, 2009
Variation of the action of erythropoiesis-stimulating agent (ESA) may modify oxidative stress in hemodialyzed (HD) patients. Our aim was to follow changes of oxidative stress during withdrawal and subsequent resumption of ESA therapy.After a 14-day suspension of epoietin-beta treatment, 11 HD patients received epoietin-beta and 10 patients darbepoietin-
Monostori Péter, Hracskó Zsuzsa, Vécseiné Karg Eszter, Szőllősi Varga Ilona, Kiss Zoltán, Boros Tímea, Kiss Éva, Haszon Ibolya, Papp Ferenc, Sümegi Viktória, Bereczki Csaba, Túri Sándor   +11 more
openaire   +3 more sources

Anemia and impaired stress-induced erythropoiesis in aceruloplasminemic mice

Blood Cells, Molecules, and Diseases, 2004
Ceruloplasmin (Cp) is an abundant, copper-containing plasma protein with an important role in iron homeostasis. Patients with hereditary Cp deficiency have iron deposits in liver and other organs, consistent with impaired iron flux. The mild anemia reported in some patients suggests a possible role for Cp in iron delivery to red cell precursors during ...
Srujana, Cherukuri, Nicholas A, Tripoulas, Saul, Nurko, Paul L, Fox   +3 more
openaire   +2 more sources

The Role of p38a in stress erythropoiesis

2009
Während der Erythropoiese von Säugetieren entwickeln sich hämatopoetische Stammzellen zu Erythroblasten, welche zusammen mit Makrophagen Blutinseln bilden und in der terminalen Differenzierung zu Erythrozyten schließlich den Nukleus ausstoßen. In der Stresserythropoiese, wie zum Beispiel während fötaler Entwicklung oder Anämie, nimmt die Produktion von
openaire   +1 more source

Foxo3 transcription factor regulates oxidative stress in in vivo erythropoiesis

Blood Cells, Molecules, and Diseases, 2006
Abstract Reactive oxygen species (ROS) such as superoxide anions and hydrogen peroxides are byproducts of normal oxidative metabolism that play an important role in regulating the proliferation of many cell types including hematopoietic cells.
Marinković, Dragan, Zhang, Xin, Brugnara, Carlo, Ghaffari, Saghi   +3 more
openaire   +3 more sources

Fetal erythropoiesis in stress hematopoiesis.

Experimental hematology, 1983
Fetal erythropoiesis occurs during chronic bone marrow failure, or during recovery from marrow suppression. Fetal erythrocytes have HB F, with more G gamma than A gamma chains, "i" antigen, large MCV, characteristic enzyme levels, low carbonic anhydrase, low HB A2, and short life span. Many of these fetal characteristics are present in the red cells of
openaire   +1 more source

Osteoblast-Derived Erythroferrone Regulates Stress Erythropoiesis

Blood
Erythroferrone (ERFE) secreted by erythroblasts is known as an erythroid regulator of iron metabolism through hepcidin suppression. Our earlier studies indicated that ERFE highly expresses in osteoblasts and Erfe-/- mice displayed decreased bone mineral density, indicating the osteoprotective effect of ERFE in bone
Pinanong Na Phatthalung, Yelena Ginzburg, Gabrielle van Caloen, Marina Planoutene, Anisa A. Gumerova, Ronit Witztum, Eva Ingber, Farhath Sultana, Funda Korkmaz, Maayan Levy, Tony Yuen, Mone Zaidi   +11 more
openaire   +1 more source

Lipid-Dependent Roles for SAMD14 in Stress Erythropoiesis

Blood
Sterile alpha motif-containing protein 14 (SAMD14) is upregulated in mouse models of anemia and its absence leads to lethality after severe hemolytic anemia, without affecting steady-state hematopoiesis. To elucidate how SAMD14 expression helps mice recover from acute stress, we conducted a global phosphoproteomic ...
Pooja Roy, Suhita Ray, Suyong Choi, Nicholas Woods, Kyle J Hewitt   +4 more
openaire   +1 more source

The Biology of Stress Erythropoiesis and Erythropoietin Production^a

Annals of the New York Academy of Sciences, 1994
C E, Bozzini, R M, Alippi, A C, Barceló, M I, Conti, C, Bozzini, C E, Lezon, M I, Olivera   +6 more
openaire   +2 more sources