Results 211 to 220 of about 2,700,982 (237)

Sappanwood extract modulates hepatic structure-function in hepatomegaly and hepcidin related iron regulatory pathways in a phenylhydrazine induced hemolytic anemia rat model relevant to thalassemia. [PDF]

Animal Model Exp Med
Pratama MI, Safitri R, Malini DM, Syamsunarno MRAA, Ghozali M, Madihah M.   +5 more
europepmc   +1 more source

Lipid metabolism transcriptomic signature of defective erythropoiesis in Diamond Blackfan anemia syndrome. [PDF]

Blood Adv
Deng K, Wang Y, Min JC, Liu X, Ueharu H, Myers G, Yu L, Hammoud S, Adam A, Saba R, Natogi V, Drysdale C, Chen B, Yee J, Kitzman JO, Lyssiotis CA, Mishina Y, Jones M, Kaartinen V, Guan Y, Khoriaty R, Engel JD, Singh SA.   +22 more
europepmc   +1 more source

TMEM187 is a novel brakelike modulator in the regulation of erythropoiesis.

Blood
Liu Y, Zhang W, Cai J, Zhou D, Zhao H, Dong W, Zhao B, Lu Y, Hao S, Ding Y, Jiang N, Qiao T, Li K.   +12 more
europepmc   +1 more source

Molecular insights into stress erythropoiesis

Current Opinion in Hematology, 2007
In addition to its essential role in baseline erythropoiesis, the hormone erythropoietin drives the erythropoietic response to hypoxic stress. A mechanistic understanding of stress erythropoiesis would benefit multiple clinical settings, and may aid in understanding leukemogenesis.The spectrum of progenitors targeted by the erythropoietin receptor is ...
Socolovsky, Merav
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Effects of psychological stress on serum iron and erythropoiesis

International Journal of Hematology, 2008
There are about one billion patients with iron deficiency anaemia all over the world. Recently, researchers have reported successively that stress can cause decrease of serum iron, in consistent with our studies showing that heat exposure and acceleration stress led to significant decrease of serum iron in rats.
Chunlan, Wei, Jian, Zhou, Xueqiang, Huang, Min, Li   +3 more
exaly   +3 more sources

Defining the Processes Regulating Stress Erythropoiesis [PDF]

, 2020
The current thesis aimed at broadening our understanding of the processes governing stress erythropoiesis. Phenylhydrazine-induced haemolytic anaemia was utilised as a mouse model of acute stress erythropoiesis. An unbiased whole transcriptome analysis followed by a multi-parametric flow cytometry assessment of splenic stress erythroid precursors was ...
Colonne, Chanukya
openaire   +2 more sources

Metabolic Regulation during Stress Erythropoiesis 2257677

The Journal of Immunology
Abstract Introduction During Anemia of Inflammation (AI), pro-inflammatory cytokines skew hematopoiesis towards myelopoiesis and impair homeostatic steady-state erythropoiesis, thus decreasing overall erythroid output.
Sara Trimidal, Vidhi Pareek, Baiye Ruan, Rajeswaran Mani, Robert Paulson   +4 more
openaire   +2 more sources

Macrophages Provide Essential Support for Erythropoiesis, and Extracellular ATP Contributes to a Erythropoiesis-Supportive Microenvironment during Repeated Psychological Stress [PDF]

International Journal of Molecular Sciences, 2023
Psychological stress is a significant contributor to various chronic diseases and affects multiple physiological processes including erythropoiesis. This study aimed to examine the tissue-specific contributions of macrophages and extracellular ATP, as a ...
Sanja Vignjevic Petrinović, Maja Milosevic, Slavko Mojsilovic   +2 more
exaly   +2 more sources

Chronic psychological stress activates BMP4‐dependent extramedullary erythropoiesis [PDF]

Journal of Cellular and Molecular Medicine, 2014
Psychological stress affects different physiological processes including haematopoiesis. However, erythropoietic effects of chronic psychological stress remain largely unknown.
Vladan Cokic, Slavko Mojsilovic
exaly   +2 more sources

The Stress of Erythropoiesis

Science's STKE, 2000
It has been thought that the major function of p38, a stress-activated protein kinase of the MAP kinase family, is to activate stress responses during inflammation. However, Tamura et al . report that when mice lack p38α, those that survive are anemic and display defective erythropoiesis.
openaire   +2 more sources