Results 191 to 200 of about 2,700,982 (237)
Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley +1 more source
Shear‐Responsive Red Blood Cell Carriers for Targeted Drug Delivery to Constricted Arteries
Red blood cells are harnessed as mechanoresponsive carriers that exploit the elevated shear stress of stenotic arteries to transiently open membrane pores and release encapsulated therapeutics selectively at sites of arterial narrowing. By coupling vascular hemodynamics with RBC membrane mechanics, a hemodynamically activated platform for localized ...
Danielle Nemcovsky Amar +10 more
wiley +1 more source
Dried tomato pomace powder is evaluated as a functional feed additive for Sonali chickens under tropical conditions. Dietary supplementation up to 6% improves growth performance, feed efficiency, carcass yield, serum lipid profile and economic return without adverse haematological effects.
Md. Ahsan Habib +8 more
wiley +1 more source
ABSTRACT Background Range grazing remains the principal feed resource for goats in smallholder production systems, particularly in regions where range grazing and intensive concentrate‐based systems coexist. However, expanding cropland has reduced the availability of grazing lands and shifted production toward concentrate‐based feeding systems ...
Selamu Abraham +2 more
wiley +1 more source
Anemia of Inflammation in Solid Tumor Patients and Practical Education for Oncologists and Nurses
Tumor‐ and immune‐derived cytokines including IL‐6, IL‐1β, TNF‐α, TGF‐β, IL‐10, and IFN‐γ drive anemia of inflammation: IL‐6/TNF‐α upregulate hepatic hepcidin to block iron export, while other cytokines suppress erythropoiesis and shorten red cell survival.
Xiaoyan Si +5 more
wiley +1 more source
The Calreticulin control of human stress erythropoiesis is impaired by JAK2V617F in polycythemia vera. [PDF]
Falchi M +8 more
europepmc +1 more source
Oxygenaging: A Physiological Framework for Geroscience
Mechanisms of aging disrupt oxygen homeostasis through three converging processes: oxygen‐cascade impairment, microvascular dysfunction, and molecular maladaptation. “Oxygenaging” integrates these domains to explain how declining oxygen delivery and utilization drive mitochondrial instability and amplify the effect of the hallmarks of aging.
Stefano Donega +6 more
wiley +1 more source
Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo +6 more
wiley +1 more source
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley +1 more source
Micronutrient Networks in Nutritional Anemia: A Narrative Review Beyond Pathophysiology, Diagnosis, and Management of Iron Deficiency. [PDF]
Chougule S +6 more
europepmc +1 more source

