Results 101 to 110 of about 1,074,800 (318)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Beacons of Excellence in Stress Prevention
NoThis report describes the work of Robertson Cooper Ltd and UMIST to identify good practice in stress prevention and then identify organisations within the UK that could be called beacons of excellence in comparison to this model.
Gurr, E. +3 more
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Analysis and optimization of multiple factors influencing fracturing induced stress field
The induced stress field caused by hydraulic fracturing plays a key role in controlling the formation characteristics of fractures and is the essential prerequisite for optimal design of fracturing parameters.
Bing Guan +4 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Psychobiological responses to critically evaluated multitasking
In order to understand psychobiological responses to stress it is necessary to observe how people react to controlled stressors. A range of stressors exist for this purpose; however, laboratory stressors that are representative of real life situations ...
Mark A. Wetherell +3 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Evaluation of the Oxidative Stress in Chronic Alcoholics
The present study was conducted to assess the activity of Gamma Glutamyl Transferase (GGT) and its association with oxidative stress in alcoholics.Sixty male alcoholics with a history of alcohol abuse for more than five years were the subjects of this study.
Mamta Singh +4 more
openaire +3 more sources
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Objective negative evaluation level, perceived stress, and autonomic reactivity in a lab-based stress induction : a test of moderated mediation in a three-variable system [PDF]
Objective stress exposure, the impartial level of threat, and perceptions of stress, the level of threat a person endorses feeling, are important constructs in biopsychosocial research on internalizing psychopathology risk.
Suresky, Rachel E +1 more
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