Results 121 to 130 of about 1,074,800 (318)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Stress evaluation of railroad forged wheels by ultrasonic testing

, 2015
Many railroads and research institutes have developed nodestructive testing methods in order to prevent accidents and remove the wheels from service before they fail.
Andrino, MH, Minicuci, DJ, Santos, FD, dos Santos, AA   +3 more
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The comparison of three dimensional and two dimensional evaluation of varus/valgus stress X-rays following total knee arthroplasty

Journal of Orthopaedic Surgery and Research
Purpose The purpose of this study was to compare three-dimensional (3D) and two-dimensional (2D) evaluation of the stress X-rays following total knee arthroplasty (TKA).
Hiroki Hijikata, Tomoharu Mochizuki, Keisuku Maeda, Osamu Tanifuji, Go Omori, Noriaki Yamamoto, Hiroyuki Kawashima   +6 more
doaj   +1 more source

First study on stress evaluation and reduction in hospitalized cats after neutering surgery. [PDF]

Vet World, 2022
Klintip W, Jarudecha T, Rattanatumhi K, Ritchoo S, Muikaew R, Wangsud S, Sussadee M.   +6 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Rockburst grade evaluation and parameter sensitivity analysis based on SSA-PNN framework: Considering rock mass strength.

PLoS ONE
The occurrence of rockburst is closely related to the strength and stress conditions of rock mass. The Lalin Railway tunnel in China was taken as an example, the strength and stress parameters of rock mass at 22 rockburst locations were obtained by using
Xiaoyan Zhou, Yimin Jiang, Zhenyi Wang, Yalei Wang   +3 more
doaj   +1 more source

Oxidative Stress Evaluation in Dogs Affected with Canine Monocytic Ehrlichiosis. [PDF]

Antioxidants (Basel), 2022
Pugliese M, Biondi V, Merola G, Landi A, Passantino A.   +4 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Stress evaluation in paediatric patients during dental procedures

openIntroduzione Lo stress nei pazienti pediatrici rappresenta una delle principali barriere alla riuscita del trattamento odontoiatrico, con conseguenti difficoltà nella gestione comportamentale e un potenziale evitamento delle cure nel lungo periodo ...
GONÇALVES DE FREITAS, JULIA
core  

Using salivary amylase to measure stress caused by urinating in diapers

, 2011
This article focuses on using salivary amylase levels to objectively measure patient stress caused by urinating in diapers. The study included 16 female students from Meiji University of Integrative Medicine.
Tokushige, Atsuko, Yamamoto, Miwa
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