Results 141 to 150 of about 1,074,800 (318)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Evaluation for salt stress tolerance of pepper genotypes to be used as rootstocks [PDF]

, 2013
[EN] Salinity is a major environmental constraint on crop productivity and grafting can be a sustainable strategy to enhance plant tolerance under adverse growth conditions.
Calatayud, Ángeles, López Galarza, Salvador Vicente, Penella, Consuelo, Gorbe, Elisa, Nebauer, Sergio G., San Bautista Primo, Alberto   +5 more
core  

Adult attachment and love psychological stress among college students: the mediating role of core self-evaluation and the moderating role of meaning in life

BMC Psychology
Background With college students going into dating relationships, dating partners become their new attachment figures. We aimed to investigate the relationship between adult attachment, and love psychological stress among college students, which also ...
Minghua Song, Xianman Hu, Shen Liu
doaj   +1 more source

Effects of Nature-Based Intervention in Occupational Health Care on Stress - A Finnish Pilot Study Comparing Stress Evaluation Methods. [PDF]

J Multidiscip Healthc, 2022
Lipponen M, Hallikainen V, Kilpeläinen P.   +2 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Thermoelastic stress analysis of laminated composite materials

, 2009
In this work thermoelastic stress analysis (TSA) is used to obtain quantitative stress/strain data from a variety of multi-directional laminated composites. In order to interpret the thermoelastic signal correctly the source of the thermoelastic response
Sambasivam, Shamala
core  

Oxidative Stress Evaluation in Ischemia Reperfusion Models: Characteristics, Limits and Perspectives. [PDF]

Int J Mol Sci, 2021
Chazelas P, Steichen C, Favreau F, Trouillas P, Hannaert P, Thuillier R, Giraud S, Hauet T, Guillard J.   +8 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The evaluation of the stress resistance of medical professionals present in the flooded area in the city of Krymsk and post-traumatic stress syndrome

Кубанский научный медицинский вестник, 2015
The observations were being carried out on 186 medical professionals who were sent to the flooded area-the city of Krymsk, and on 340 people who were already there.
A. V. Burlutskaya, Y. A. Prosolenko, E. A. Malysheva, A. V. Abushkevich, E. G. Potyagailo, V. G. Abushkevich   +5 more
doaj  

FIB-DIC Residual Stress Evaluation in Shot Peened VT6 Alloy Validated by X-ray Diffraction and Laser Speckle Interferometry. [PDF]

Nanomaterials (Basel), 2022
Somov PA, Statnik ES, Kan Y, Pisarev VS, Eleonsky SI, Ozherelkov DY, Salimon AI.   +6 more
europepmc   +1 more source