Results 181 to 190 of about 129,858 (349)

Evidence That G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress [PDF]

, 2016
Alicia K. Byrd, Boris Zybailov, Leena Maddukuri, Jun Gao, John C. Marecki, Mihir Jaiswal, Matthew Bell, Wezley C. Griffin, Megan R. Reed, Shubeena Chib, Samuel G. Mackintosh, Angus M. MacNicol, Giulia Baldini, Robert L. Eoff, Kevin D. Raney   +14 more
openalex   +1 more source

GSK3β‐Regulated Lipolysis is Required for Histone Acetylation and Decidualization in Early Pregnancy

Advanced Science, EarlyView.
Uterine Gsk3b knockout impairs decidual cell terminal differentiation by causing lipid droplet accumulation. GSK3β phosphorylates RNF213 to promote its lysosomal degradation, thereby enhancing lipolysis. The released fatty acids undergo β‐oxidation to generate acetyl‐CoA, which modulates histone acetylation and regulates decidual cell terminal ...
Peiran Wang, Yedong Tang, Xueling Zhao, Yu Ni, Hualan Zhou, Enhao Zhang, Gaizhen Li, Han Cai, Yinan Wang, James R. Woodgett, Wenbo Deng, Haibin Wang, Zhongxian Lu, Haili Bao, Shuangbo Kong   +14 more
wiley   +1 more source

Stereological Estimation of Granule Cell Number and Purkinje Cell Volume in the Cerebellum of Noise-Exposed Young Rat

Iranian Journal of Medical Sciences, 2015
In spite of the existing reports on behavioural and biochemical changes related to the cerebellum due to noise stress, not much is known about the effect of noise stress on the neuronal changes in the cerebellum.
Mohammad Hosseini-Sharifabad, Abdoreza Sabahi   +1 more
doaj  

Liquid–liquid phase separation in diseases

MedComm
Liquid–liquid phase separation (LLPS), an emerging biophysical phenomenon, can sequester molecules to implement physiological and pathological functions.
Xinyue Zhang, Lin Yuan, Wanlu Zhang, Yi Zhang, Qun Wu, Chunting Li, Min Wu, Yongye Huang   +7 more
doaj   +1 more source

Preservation of Complex Multiphase Architectures in Polymer‐Based Artificial Cells by Photo‐Crosslinking

Advanced Science, EarlyView.
Phase separation organizes cellular components, yet stabilizing such dynamic structures in artificial cells remains challenging. A photo‐crosslinking approach is presented that prolongs the lifetime of different structures in coacervate‐based artificial cells while maintaining dynamic formation.
Madelief A. M. Verwiel, Alexander B. Cook, Yiǧitcan Sümbelli, Nadia A. Erkamp, Jan C. M. van Hest   +4 more
wiley   +1 more source

Regulation of stress granules and P‐bodies during RNA virus infection

, 2013
Richard E. Lloyd
openalex   +2 more sources

RNase L Amplifies Interferon Signaling by Inducing Protein Kinase R-Mediated Antiviral Stress Granules

, 2020
Praveen Manivannan, Mohammad Adnan Siddiqui, Krishnamurthy Malathi   +2 more
openalex   +1 more source

Super-Resolution Fluorescence Imaging Reveals Nanoscale Organization of Stress Granule [PDF]

, 2014
Ko Sugawara, Kohki Okabe, Akihiko Sakamoto, Takashi Funatsu   +3 more
openalex   +1 more source

Editorial: The Dynamics of Stress Granules [PDF]

Frontiers in Cell and Developmental Biology, 2021
Subhash Mehto, Beidong Liu, Beidong Liu, Beidong Liu, Ronggui Hu, Ronggui Hu, Santosh Chauhan   +6 more
openaire   +3 more sources

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source