Results 181 to 190 of about 70,909 (261)

Non-transcriptional activity of IRF3 promotes liver fibrosis and stress granule assembly via a dsRNA-TLR3-dependent pathway in hepatic stellate cells. [PDF]

Hepatology
Travers J, Zhang Y, Cajigas-Du Ross CK, Huang E, McMullen MR, Wu J, Paouri E, Davalos D, Wu X, Pathak V, Rotroff DM, Nagy LE.   +11 more
europepmc   +1 more source

Type I interferon drives dysfunction of a distinct CD8+ HLA‐DRB1+ T cell subset in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long, Elio Carmona, Mikhail G Dozmorov, Amr H Sawalha   +3 more
wiley   +1 more source

Stress granule dynamics orchestrate colitis-to-cancer transition via TOM1-mediated disassembly and driven oncogenesis in response to inflammatory oxidative stress. [PDF]

Redox Biol
Wan Z, Qian M, Yu J, Shu T, Wang D, Liang X, Chen R, Shi B, Cui H, Chen Z, Jiang J.   +10 more
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

A stress granule-associated RNA-binding protein FAM120A drives cisplatin resistance in non-small cell lung cancer. [PDF]

J Biochem
Hayai S, Suzuki MM, Iijima K, Shinjo K, Murofushi Y, Xie J, Nishimura T, Ishii M, Kondo Y.   +8 more
europepmc   +1 more source

Scaling of Planar Sodium‐Nickel Chloride Battery Cells to 90 cm2 Active Area

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
Large planar Na β′′ alumina electrolytes are prepared by tape‐casting and die‐pressing. These ceramic electrolytes are used to prepare planar sodium‐nickel chloride cells with 90 cm2 active area, providing a high capacity of 7 Ah. Successful cell cycling is demonstrated at 300 °C at rates up to C/4 (20 mA cm−2) for a cumulative capacity of 3.6 Ah cm−2.
T. Lan, E. Svaluto‐Ferro, N. Kovalska, G. Graeber, F. Vagliani, D. Basso, A. Turconi, M. Makowska, G. Blugan, C. Battaglia, M. V. F. Heinz   +10 more
wiley   +1 more source

Connecting the Dots: Stress Granule and Cardiovascular Diseases. [PDF]

J Cardiovasc Transl Res
Yang G, Wang Y, Guo J, Rui T.
europepmc   +1 more source

Cytosolic Immunostimulatory DNA Ligands and DNA Damage Activate the Integrated Stress Response, Stress Granule Formation, and Cytokine Production. [PDF]

Cells
Devale T, Katuri L, Mishra G, Acharya A, Manivannan P, Hibbard BR, Malathi K.   +6 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Stress granule dynamics govern TOR reactivation and growth recovery during post-heat stress adaptation. [PDF]

Sci Adv
Zhong Z, Yang S, Liu D, Liu Z, Zhao W, Shen X, Wang F, Liu Y, Xu T, Fang X, Xiong Y.   +10 more
europepmc   +1 more source