Results 131 to 140 of about 162,836 (295)

Charge Pattern Matching as a "Fuzzy" Mode of Molecular Recognition for the Functional Phase Separations of Intrinsically Disordered Proteins

open access: yes, 2017
Biologically functional liquid-liquid phase separation of intrinsically disordered proteins (IDPs) is driven by interactions encoded by their amino acid sequences.
Brady, Jacob P.   +3 more
core   +1 more source

RNA Granules and Stress Granules in Virus Systems

open access: yesJournal of Bacteriology and Virology, 2012
Viruses initiate a number of cellular stress responses and modulate gene regulation and compartmentalization of RNA upon infection to be successful parasites. Virus infections may induce or impair stress granule (SG) formation to maximize replication efficiency.
openaire   +1 more source

Anti‐Slip Material‐Based Strategies and Approaches

open access: yesAdvanced Materials Technologies, EarlyView.
This review highlights the principle mechanisms of slipping at the microscale, linking contact mechanics with a friction behavior model for surface interfaces. Main strategies to develop anti‐slip properties to the surfaces are discussed alongside standardized testing approaches.
Sogand Abbaspoor‐Zanjani   +3 more
wiley   +1 more source

Ataxin-2-like is a regulator of stress granules and processing bodies.

open access: yesPLoS ONE, 2012
Paralogs for several proteins implicated in neurodegenerative disorders have been identified and explored to further facilitate the identification of molecular mechanisms contributing to disease pathogenesis.
Christian Kaehler   +6 more
doaj   +1 more source

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li   +7 more
wiley   +1 more source

N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion.

open access: yesPLoS ONE, 2013
Iron is critical for cellular proliferation and its depletion leads to a suppression of both DNA synthesis and global translation. These observations suggest that iron depletion may trigger a cellular "stress response".
Darius J R Lane   +5 more
doaj   +1 more source

Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1

open access: yesmBio, 2015
Stress granules (SGs) are dynamic cytoplasmic repositories containing translationally silenced mRNAs that assemble upon cellular stress. We recently reported that the SG nucleating protein G3BP1 promotes antiviral activity and is essential in double ...
Lucas C. Reineke   +4 more
doaj   +1 more source

Elastomers Combining Damping Efficiency With Rapid Recovery

open access: yesAdvanced Materials Technologies, EarlyView.
Double network granular elastomers (DNGEs) combine high energy dissipation under both cyclic loading and high impact with rapid shape recovery. 3D printing enables the production of complex, customizable structures with tailored performance. Recyclable DNGEs retain their properties over multiple recycling cycles.
Eva Baur, Alain Molleyres, Esther Amstad
wiley   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

open access: yesAdvanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

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