Results 191 to 200 of about 2,813,474 (315)

TRIM21 blocks DDX3X-driven stress granule formation during Mycobacterium tuberculosis infection via a non-canonical E3 ligase mechanism

Ruiyao Xu, Mengru Lu, Gaoyan Wang, Ximeng Zhang, Yuxing Huang, Yu Wang, Qing Yu, Yaxuan Wang, Dan Chen, Yunlong Hu, Chenyan Shi, Yi Cai, Li Fu, Xinchun Chen, Youchao Dai   +14 more
openalex   +2 more sources

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

The E3 ligase MKRN2 prevents DRiP accumulation in stress granules and maintains granulostasis. [PDF]

EMBO Rep
Amzallag E, Danino YM, Secco V, Carra S, Hornstein E.   +4 more
europepmc   +1 more source

Magneto‐Sono‐Enhanced Nanozyme Catalysis Drives ROS‐Mediated Pathogen Killing and Mitophagy‐Linked Inflammation Control in Bacterial Pneumonia

Advanced Science, EarlyView.
Nebulized BN@NF nanozymes integrate boron nanosheets with Nd‐doped iron phosphide to form a sono‐magneto‐responsive Z‐scheme heterostructure. Under ultrasound and magnetic activation, BN@NF amplifies ROS generation, eradicates bacteria, disrupts biofilms, and reshapes pulmonary inflammation through NF‐κB suppression, mitophagy promotion, and M1‐to‐M2 ...
Xiaofeng Luo, Yundi Wu, Shuai Zhang, Huanran Qu, Shiyang Shao, Jianqiang Chen, Xilong Wu   +6 more
wiley   +1 more source

Stress granules formed during infections with RNA viruses have significant virus-specific differences in generation and composition. [PDF]

PLoS Biol
Lang RM, Steiner S, Kelly J, Uldry AC, Dave P, Braga-Lagache S, Chao J, Heller M, Barut GT, Thiel V.   +9 more
europepmc   +1 more source

Ivermectin Inhibits Stress Granule Clearance by Blocking the De Novo Synthesis of Hsp70 in Neuroblastoma Cells

Siwei Chu, Elizabeth P. Anim, Reyhaneh Salehi-Tabar, John H. White, Ursula Stochaj   +4 more
openalex   +1 more source

miRNA-34b overexpression alleviates neuromyelitis optica spectrum disorders by regulating the TIA-1-stress granule pathway [PDF]

Yan Dai
openalex   +1 more source

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

Advanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken, Paula Beltran Lobo, Yunzhao Wu, Lyla A. Rowe, Emre Fertan, Cara L. Croft, Maria Jimenez‐Sanchez, Dezerae Cox, David Klenerman   +8 more
wiley   +1 more source

Chlorination‐Driven BODIPY Fluorescent Probes for the Selective Monitoring of Myeloperoxidase Activity in Cells and Inflamed Mouse Models

Angewandte Chemie, EarlyView.
A meso‐carboxamide‐substituted BODIPY fluorescent probe reports myeloperoxidase (MPO) activity via electrophilic chlorination by MPO‐derived HOCl, generating a highly emissive chlorinated product with a ca. 40 nm bathochromic shift. Applications in quantitative MPO assays, cellular imaging of MPO‐derived HOCl, redox‐dependent discrimination of cancer ...
Siyoung Cho, Yongyang Luo, Jeehyeon Bae, Youngmi Kim   +3 more
wiley   +2 more sources

A composition-matching algorithm, MatchIDR, identifies prion-like domains that localize to stress granules. [PDF]

Protein Sci
Cascarina SM, Paul KR, Ford LL, Ross ED.
europepmc   +1 more source