Results 281 to 290 of about 4,058,220 (323)

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Stress granules and cell death: crosstalk and potential therapeutic strategies in infectious diseases. [PDF]

Cell Death Dis
Huang HS, Chen L, Chi JX, Lai SY, Pi J, Shao YM, Xu JF.   +6 more
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Compositional analysis of yellow fever virus induced stress granules reveals a functional connection to mitochondrial homeostasis

Jakob C, Streicher F, Lopez-Nieto M, Eke L, Lee D, Wu J, Taylor JP, Matia-Gonzalez AM, Jouvenet N, Locker N.   +9 more
europepmc   +1 more source

Chemotherapeutic drug-triggered AEP-cleaved G3BP1 orchestrates stress granules/nucleoli/mitochondria in osteosarcoma. [PDF]

Bone Res
Shi Z, Zhao J, Lv Q, Liao K, Cao L, Yang J, Wang M, Zhou L, Xu H, Ge J, Qiu Y, Chen J, Chen J, Ma C, Lin Y.   +14 more
europepmc   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease

Exploration, EarlyView.
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren, Zhaoxu Wu, Min Li, Yaqin Du, Hong Zhou, Yazhu Quan, Mengyao Xiong, Yiming Wang, Zhiwei Qiu, Shuai Zhu, Xiaowei Li, Jinzhao He, Cai Gao, Hui Cai, Tingting Li, Baoxue Yang   +15 more
wiley   +1 more source

Stress granules attenuate protein nanoparticle induced osmotic imbalance via membrane potential restoration. [PDF]

Sci Rep
Song X, Zhou W, Shi Y, Zhao Y, Huang K, Guo Y, Zhao H, Li Y, Guo J.   +8 more
europepmc   +1 more source

Rheological and Textural Properties of Clean‐Label 3D‐Printed Traditional Thai Dessert

Food Bioengineering, EarlyView.
ABSTRACT This study aimed to develop a clean‐label 3D‐printable food ink using a formulation based on Khanom Piak Poon, a traditional Thai dessert, enriched with carrot powder (CP) for enhanced nutritional value. Unlike conventional food printing inks that contain additive hydrocolloids, this ink relies on the natural reactions between starch, sugar ...
Anucha Pramuan, Phennapha Saokham, Chanawat Nitatwichit, Yardfon Tanongkankit, Saranyapak Chamnan, Suthathip Wongpansua, Jaturapatr Varith   +6 more
wiley   +1 more source

Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology. [PDF]

Sci Adv
Mohan HM, Fernandez MG, Huang C, Lin R, Ryou JH, Seyfried D, Grotewold N, Barget AJ, Whiteley AM, Basrur V, Mosalaganti S, Paulson HL, Sharkey LM.   +12 more
europepmc   +1 more source