Results 261 to 270 of about 162,836 (295)

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Correlative Raman and immunofluorescence imaging reveals different protein abundance between stress granules induced by oxidative damage. [PDF]

J Inorg Biochem
Gery KL, Ramos S, Lee JC.
europepmc   +1 more source

Compositional analysis of yellow fever virus induced stress granules reveals a functional connection to mitochondrial homeostasis

Jakob C, Streicher F, Lopez-Nieto M, Eke L, Lee D, Wu J, Taylor JP, Matia-Gonzalez AM, Jouvenet N, Locker N.   +9 more
europepmc   +1 more source

The recruitment of the A-type cyclin TAM to stress granules is crucial for meiotic fidelity under heat. [PDF]

Sci Adv
De Jaeger-Braet J, Hartmann M, Böttger L, Yang C, Hamada T, Hoth S, Feng X, Weingartner M, Schnittger A.   +8 more
europepmc   +1 more source

Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules. [PDF]

Adv Sci (Weinh)
Liu X, Liu X, Xue M, Xiao Y, Chen Y, Qiu R, Wu D, Zhou Y, Wang J, Yuan Y, Yu L, Shi T, Li Y, Su H, Chen H, Liu Y, Huang K, Zheng L.   +17 more
europepmc   +1 more source

Small-molecule dissolution of stress granules by redox modulation benefits ALS models. [PDF]

Nat Chem Biol
Uechi H, Sridharan S, Nijssen J, Bilstein J, Iglesias-Artola JM, Kishigami S, Casablancas-Antras V, Poser I, Martinez EJ, Boczek E, Wagner M, Tomschke N, de Jesus Domingues AM, Pal A, Doeleman T, Kour S, Anderson EN, Stein F, Lee HO, Zhang X, Fritsch AW, Jahnel M, Fürsch J, Murthy AC, Alberti S, Bickle M, Fawzi NL, Nadler A, David DC, Pandey UB, Hermann A, Stengel F, Davis BG, Baldwin AJ, Savitski MM, Hyman AA, Wheeler RJ.   +36 more
europepmc   +1 more source

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Metabolites control stress granule disassembly

Nature Cell Biology, 2021
Cells respond to stimuli by reorganizing their contents into subcellular structures. New research demonstrates that yeast pyruvate kinase Cdc19 interacts with fructose-1,6-bisphosphate to coordinate disassembly of stress granules. These findings reveal how proteins can directly sense the cellular energy state to facilitate adaptive reorganization.
Christopher M. Jakobson, Daniel F. Jarosz   +1 more
openaire   +2 more sources

Stress granules plug holes

Science Signaling, 2023
Ruptures in lysosomal membranes stimulate the formation of stress granules that plug the holes to enable repair.
openaire   +2 more sources

Stress granules: regulators or by‐products?

The FEBS Journal, 2021
Cells have to deal with conditions that can cause damage to biomolecules and eventually cell death. To protect against these adverse conditions and promote recovery, cells undergo dramatic changes upon exposure to stress. This involves activation of signaling pathways, cell cycle arrest, translational reprogramming, and reorganization of the cytoplasm.
Daniel Mateju, Jeffrey A. Chao
openaire   +2 more sources

Yeast stress granules at a glance

Yeast, 2021
AbstractThe formation of stress granules (SGs), membrane‐less organelles that are composed of mainly messenger ribonucleoprotein assemblies, is the result of a conserved evolutionary strategy to cellular stress. During their formation, which is triggered by robust environmental stress, SGs sequester translationally inactive mRNA molecules, which are ...
Tomas Grousl, Jana Vojtova, Jiri Hasek, Tomas Vomastek   +3 more
openaire   +2 more sources