Results 271 to 280 of about 2,813,474 (315)

Hyperactive KIF5A in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT The highly polarised morphology of neurons and the sheer length of their axons make transport of cargoes throughout the cell a formidable task. Decades of evidence obtained from genetic studies on patients and animal models highlight deficits in axonal transport as a recurrent cause, or early contributing factor, in a plethora of ...
David Villarroel‐Campos, James N. Sleigh   +1 more
wiley   +1 more source

Tetramethylthiuram disulfide induces stress granules and DNA damage through oxidative stress in human lung epithelial cells. [PDF]

Anim Cells Syst (Seoul)
Lin M, Lee S, Gwak J, Cha J, Hong S, Kim EM, Kim KK.   +6 more
europepmc   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

RNA helicase DDX6 governs ASC speck formation in P-bodies and the transition to stress granules via phase separation during inflammasome activation. [PDF]

Cell Discov
Mao R, Liu Y, Fan Z, Li Y, Yang L, Xie Q, Dong HP, Bi M, Gao C, Yang Z, Xu T, Qi X.   +11 more
europepmc   +1 more source

C9orf72 ALS-causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules. [PDF]

FEBS Lett
Bilican S, Nabawi Y, Zhang WH, Petrovic D, Wehrmann M, Muñoz-García S, Koyuncu S, Vilchez D.   +7 more
europepmc   +1 more source

Exploring Potential Stress Granule-Related Biomarkers in Childhood Asthma Using Integrated Bioinformatics and Machine Learning

Ya Zou, Hua Ren, Jun Zheng, Yanjie Huang
openalex   +1 more source

Stress granules promote quiescence by enhancing p21 levels and reducing phospho-Rb. [PDF]

RNA
Khong A, Ripin N, de Vasconcelos LM, Passanisi V, Spencer S, Parker R.   +5 more
europepmc   +1 more source

Stress granules confer an early vulnerability in KRAS-driven pancreatic tumorigenesis

Matías Estarás, Emma Cosialls, Gareth Pollin, Anass Berkachi, Noriyuki Nishiwaki, Gerardo Blanco, Miguel Fernández‐Bermejo, Antonio Gonzalez, Anil K. Rustgi, Gwen Lomberk, Raul Urrutia, Patricia Santofimia‐Castaño, Juan Iovanna   +12 more
openalex   +1 more source

Multi-Faceted Roles of Stress Granules in Viral Infection. [PDF]

Microorganisms
Zhao R, Li X.
europepmc   +1 more source