Results 241 to 250 of about 77,443 (288)

Protocol for multi-component reconstitution of stress granules in vitro. [PDF]

STAR Protoc
Yao Z, Liu Y, Yang P.
europepmc   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Proof of concept: targeted protein degradation of the stress granules component G3BP1 as an antiviral strategy against norovirus infection. [PDF]

Antimicrob Agents Chemother
Echavarria-Consuegra L, Goodfellow I.
europepmc   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

IGF2BP1 positively regulates CircOGDH accumulation in hypoxia induced stress granules. [PDF]

Acta Pharm Sin B
Su X, Zang J, Wang Y, Zhang S, Wu P, Chen W, Shi L, Wu Y, Deng D, Cai K, Mai H, Xu A, Lu D.   +12 more
europepmc   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

Astrocytic TIA1-Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model. [PDF]

Adv Sci (Weinh)
Fang Z, Hua X, Fan Z, Zhao J, Zhang Y, Zhang Q, Qu X, Pan S, Wan B, Yang S, Li J, Zhang X.   +11 more
europepmc   +1 more source

Simultaneous Enhancement of Mechanical and Dielectric Performance of Polypropylene Composites by Introducing an External Elastic Crystal

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A hierarchical crystalline structure for recyclable polypropylene insulation in high‐voltage cables is presented. This architecture integrates rigid isotactic polypropylene spherulites with an elastic crystalline network to balance load‐bearing capacity and ductility.
Guangwei Zhang, Zepeng Lv, Zhengbing Tian, Juntao Zhao, Dan Cao, Kai Wu, Thomas Andritsch   +6 more
wiley   +1 more source

Stress granules and organelles: coordinating cellular responses in health and disease. [PDF]

Protein Cell
Liu Y, Li Y, Zhang P.
europepmc   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source