Results 231 to 240 of about 162,836 (295)

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Stress granules: emerging players in neurodegenerative diseases. [PDF]

Transl Neurodegener
Yuan L, Mao LH, Huang YY, Outeiro TF, Li W, Vieira TCRG, Li JY.   +6 more
europepmc   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Proof of concept: targeted protein degradation of the stress granules component G3BP1 as an antiviral strategy against norovirus infection. [PDF]

Antimicrob Agents Chemother
Echavarria-Consuegra L, Goodfellow I.
europepmc   +1 more source

Positive Doping Test Linked to Crumb Rubber From Artificial Football Pitch: Case Report

Drug Testing and Analysis, EarlyView.
1,3‐DMBA was detected in urine samples of eight athletes following a doping control, resulting in one AAF and levels below WADA's MRL in seven teammates. Investigation revealed contamination from rubber infill used on the indoor artificial turf, with analysis confirming 1,3‐DMBA in the turf's crumb rubber originating from recycled tires.
Astrid Gjelstad, Geir Holden, Per Ole M. Gundersen, Yvette Dehnes, Magnus Tvedte, Maren Levernæs, Åse Kjustad Eriksson, Fredrik Lauritzen   +7 more
wiley   +1 more source

Astrocytic TIA1-Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model. [PDF]

Adv Sci (Weinh)
Fang Z, Hua X, Fan Z, Zhao J, Zhang Y, Zhang Q, Qu X, Pan S, Wan B, Yang S, Li J, Zhang X.   +11 more
europepmc   +1 more source

Toward the harmonization of bioequivalence guidelines in Europe: Commentary on the state of the art and future priorities under ICH M13A for immediate‐release oral forms

British Journal of Clinical Pharmacology, EarlyView.
Domenico Nocera, Giusi Forastiero, Andrea Logreco, Alessia Proietti, Antonio Galluccio, Carlotta Lunghi, Elisabetta Poluzzi, Fabrizio De Ponti   +7 more
wiley   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Protocol for multi-component reconstitution of stress granules in vitro. [PDF]

STAR Protoc
Yao Z, Liu Y, Yang P.
europepmc   +1 more source