Results 101 to 110 of about 1,437,569 (357)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Stress analysis and stress intensity factors for finite geometry solids containing rectangular surface cracks [PDF]

open access: yes
The line method of analysis is applied to the Navier-Cauchy equations of elastic equilibrium to calculate the displacement field in a finite geometry bar containing a variable depth rectangular surface crack under extensionally applied uniform loading ...
Gyekenyesi, J. P., Mendelson, A.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Stress Intensity Factor for Aluminum and Copper Spot Weld Joints

open access: yesJournal of Applied Science and Engineering
For decades, resistance spot welding (RSW) between aluminum and copper has encountered difficulties; however, it remains essential for modern applications.
Marwah Sabah Fakhri   +2 more
doaj   +1 more source

Theoretical and Numerical Study on Stress Intensity Factors for FRP-Strengthened Steel Plates with Double-Edged Cracks

open access: yesSensors, 2018
This paper presents a theoretical and numerical study on the stress intensity factors for double-edged cracked steel plates strengthened with fiber reinforced polymer (FRP) plates. Based on the stress intensity factor solution for infinite center-cracked
Hai-Tao Wang, Gang Wu, Yu-Yang Pang
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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