Fracture and Structural Integrity, 2019 A stress-strain state analysis of a gas turbine engine compressor disc was conducted with consideration to the accumulation of damages under various loading conditions in the temperature range.
Natalia Boychenko, Ivan Ishtyryakov
doaj +1 more source
Study of Effective Stress Intensity Factor through the CJP Model Using Full-Field Experimental Data. [PDF]
Materials (Basel), 2023 Camacho-Reyes A +3 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Predicting Stress Intensity Factor for Aluminum 6062 T6 Material in L-Shaped Lower Control Arm (LCA) Design Using Extended Finite Element Analysis. [PDF]
Materials (Basel), 2023 El Fakkoussi S +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Numerical Calculation of Stress Intensity Factor of Tooth Root Crack in the High-speed EMU Gear
Jixie chuandong, 2017 In order to research the stress intensity factor of tooth root of the high-speed EMU gear,the location of crack initiation is determined by combining the finite element method and mapping method.
Li Xiuhong +4 more
doaj
Approximate determination of stress intensity factor for multiple surface cracks [PDF]
FME Transactions, 2018 In this paper a versatile and easy to use approximate procedure was used for the estimation of mode I stress intensity factors in case of multiple surface cracks in a three dimensional elastic body, subjected to remote uniaxial tensile loading.
Kastratović Gordana +3 more
doaj
Stress Intensity Factor (SIF) Solutions and Fatigue Crack Paths in Eccentric Circumferentially Cracked Round Bar (CCRB) in Tension. [PDF]
Materials (Basel), 2023 Toribio J, Matos JC, González B.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A Review on Reductions in the Stress-Intensity Factor of Cracked Plates Using Bonded Composite Patches. [PDF]
Materials (Basel), 2022 Aabid A, Hrairi M, Ali JSM, Sebaey TA.
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