Results 41 to 50 of about 1,437,569 (357)

The Griffith Crack and the Interaction between Screw Dislocation and Semi-Infinite Crack in Cubic Quasicrystal Piezoelectric Materials

open access: yesCrystals, 2022
The Griffith crack problem and the interaction between screw dislocation and semi-infinite crack in cubic quasicrystal piezoelectric materials are studied by using the complex variable function method.
Jiandong Pi, Lianhe Li
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Thermal activation of rupture and slow crack growth in a model of homogenous brittle materials [PDF]

open access: yes, 2003
Slow crack growth in a model of homogenous brittle elastic material is described as a thermal activation process where stress fluctuations allow to overcome a breaking threshold through a series of irreversible steps.
Diu B.   +6 more
core   +5 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Stress Intensity Factors - T-Stresses - Weight Functions

open access: yes, 2008
Failure of cracked components is governed by the stresses in the vicinity of the crack tip. The singular stress contribution is characterised by the stress intensity factor K, the first regular stress term is represented by the so-called T-stress. Sufficient information about the stress state is available, if these two parameters are known Results for ...
openaire   +5 more sources

A new formulation for estimating maximum stress intensity factor at the mid plane of a SENB specimen: Study based on 3D FEA

open access: yesFracture and Structural Integrity, 2014
In this investigation, three-dimensional elastic finite element analyses have been conducted to compute the stress intensity factor (KI) in a SENB specimen with varied thickness (B) and crack-length to width ratio (a/W).
S. K. Kudari, K. G. Kodancha
doaj  

Stress and Displacement Intensity Factors of Cracks in Anisotropic Media

open access: yesInternational Journal of Applied Mechanics and Engineering, 2020
A relation connecting stress intensity factors (SIF) with displacement intensity factors (DIF) at the crack front is derived by solving a pseudodifferential equation connecting stress and displacement discontinuity fields for a plane crack in an elastic ...
S. Kuznetsov, A. Karakozova
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

STRESS INTENSITY FACTOR FOR CRACKED FLAT-ELLIPTIC CROSS-SECTION PIPE

open access: yesJixie qiangdu, 2017
As an important parameter to assess the crack pipe fracture toughness,stress intensity factor determined is particularly important. In order to solve practical engineering problems,most of them are three-dimensional crack problems,crack mouth widening ...
LI Chong, XIE YuJun
doaj  

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