Results 151 to 160 of about 588,944 (311)

Design and analysis of welded aircraft wing panels [PDF]

open access: yes, 2005
Nowadays, increasing manufacturing cost effectiveness becomes a vital condition for the commercial success of the next generation of large wide body aircrafts.
Theos, Athanasios
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Effect of crack position and loading conditions on SIF in SiC particles reinforced Al composite

open access: yesFracture and Structural Integrity, 2019
In this paper the effect of reinforcement crack position and loading conditions (in mode I) on the stress intensity factors of the Al/SiCp metal matrix composite was examined using a finite element method.
Aicha Metehri   +2 more
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

COMPLEX VARIABLE FUNCTION SOLUTIONS OF MIXED-MODE STRESS INTENSITY FACTORS FOR TWO CRACKS OF ARBITRARY LENGTH EMANATING FROM AN ELLIPTICAL HOLE

open access: yesJixie qiangdu, 2019
In order to calculate the stress intensity factors of two-dimensional cracks emanating from elliptical hole, a solution method for stress intensity factor based on Muskhelishvili complex function theory and truncated conformal mapping approach is ...
ZHU QingYu, ZHOU Rui
doaj  

Effect of random variation in input parameter on cracked orthotropic plate using extended isogeometric analysis (XIGA) under thermomechanical loading

open access: yesCurved and Layered Structures
This research introduces the Stochastic Extended Isogeometric Analysis (XIGA) method to investigate fracture behavior of isotropic and orthotropic materials under mechanical, thermal, and thermomechanical loads.
Kulkarni Nikhil M., Lal Achchhe
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Photoelastic Determination of Mixed Mode Stress Intensity Factors

open access: yes, 2009
A two dimensional finite model with inclined crack at different crack angles are being analyzed in mixed mode condition using photo elasticity method for the determination of Stress Intensity Factors.
P C Gope, V K Singh
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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