Results 151 to 160 of about 1,528,319 (313)

Sudden stretching of a four layered composite plate [PDF]

open access: yes
An approximate theory of laminated plates is developed by assuming that the extensioral and thickness mode of vibration are coupled. The mixed boundary value crack problem of a four layered composite plate is solved.
Chen, E. P., Sih, G. C.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Three-dimensional analysis of surface crack-Hertzian stress field interaction [PDF]

open access: yes
The results are presented of a stress intensity factor analysis of semicircular surface cracks in the inner raceway of an engine bearing. The loading consists of a moving spherical Hertzian contact load and an axial stress due to rotation and shrink fit.
Ballarini, R., Hsu, Y.
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

A note on a broken layer in an orthotropic laminate composite [PDF]

open access: yes
An orthotropic laminate composite containing a completely broken layer is considered. The problem is formulated in terms of integral transforms and then reduced to a singular integral equation which is solved numerically.
Arin, K.
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

A finite-element alternating method for two-dimensional Mode-1 crack configurations [PDF]

open access: yes
A finite-element alternating method is presented for 2-D Mode-1 crack problems. An analytical solution for an arbitrary polynomial normal pressure distribution applied to the crack faces is obtained and used as the basic solution in the method.
Fichter, W. B., Raju, I. S.
core   +1 more source

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