Results 131 to 140 of about 588,944 (311)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Stress intensity factors for T-butt surface cracks
, 2009 This study investigates the stress intensity factors for weld toe cracks in a double T-butt joint. There are two main phases that were carried out during the research.
Tan, Ming Hwa.
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Mode i stress intensity factors of slanted cracks
, 2017 The solutions of stress intensity factors of slanted cracks in plain strain plate are hard to find in open literature. There are some previous solutions of stress intensity factors available, however they are not studied completed except for the case of ...
Ahmad, M.H. +3 more
core
Stress Intensity Factors for Hollow Circumferentially Notched Round Bars
, 1967 Stress intensity factors are presented for a hollow circumferentially notched round bar subjected to tension, torsion, bending, and transverse shear. These previously undetermined factors are calculated from the limiting values of stress concentration ...
D. O. Harris
core +1 more source
Stress Intensity Factors - T-Stresses - Weight Functions
, 2008 Failure of cracked components is governed by the stresses in the vicinity of the crack tip. The singular stress contribution is characterised by the stress intensity factor K, the first regular stress term is represented by the so-called T-stress. Sufficient information about the stress state is available, if these two parameters are known Results for ...
openaire +5 more sources
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Two-dimensional fracture analysis of FGM under mechanical loading
Journal of Materials and Engineering Structures, 2020 This paper extends the concept to isotropic functionally graded materials and addresses fracture problems under mechanical loading. The mode-I and mixed mode stress intensity factors (SIFs) are determinate by combination between the finite element method
Imène HEBBAR +2 more
doaj
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source