Results 71 to 80 of about 2,967,034 (250)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Inversion of seismic reflection data from the Gialo Field, Sirte Basin [PDF]

, 1996
This project is concerned with the development of software to invert seismic reflection data for acoustic impedance, with application to the YY-reservoir area in Gialo Field, Sirte Basin.
BenGheit, Ali O.
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

A discrepancy-based penalty method for extended waveform inversion

, 2017
Extended waveform inversion globalizes the convergence of seismic waveform inversion by adding nonphysical degrees of freedom to the model, thus permitting it to fit the data well throughout the inversion process.
Lei Fu, William W. Symes, Symes, William W., Fu, Lei   +3 more
core   +1 more source

There is more than one way to turn a spherical cellular monolayer inside out: type B embryo inversion in Volvox globator [PDF]

, 2011
Höhn S, Hallmann A. There is more than one way to turn a spherical cellular monolayer inside out: type B embryo inversion in Volvox globator. BMC Biology.
Höhn Stephanie, Hallmann Armin, Höhn, Stephanie, Hallmann, Armin ; https://orcid.org/, Armin Hallmann, Stephanie Höhn   +5 more
core   +1 more source

Research on the application of the Quantum-behaved Particle Swarm Optimization algorithm in the inverse estimation of in-situ stress based on fault-slip fractures

Dizhi lixue xuebao
Objective  To improve the computational efficiency and accuracy of stress tensor inversion from fault-slip data, and to address the limitations of conventional grid search methods—namely, high computational cost and susceptibility to local optima—an ...
ZHOU Weiwei, FENG Yongcun, LI Xiaorong, LIU Jie, SU Feiyu, HU Han   +5 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Inversion Analysis of Stress Fields Based on the LSTM–Attention Neural Network

Applied Sciences
Conventional geostress methods of measurement cannot reveal an accurate geostress field distribution in an engineering area, limited by both cost and prevailing geological conditions. This study introduces an improved LSTM–Attention neural network for in
Jianxin Wang, Liming Zhang, Junyu Sun
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source