Elasto-Plastic Fatigue Crack Growth Behavior of Extruded Mg Alloy with Deformation Anisotropy Due to Stress Ratio Fluctuation. [PDF]
Materials (Basel), 2022 Masuda K +4 more
europepmc +1 more source
DEVELOPMENT OF AN ADVANCED HIGH PRESSURE RATIO TRANSONIC FAN STAGE. PART-I: DESIGN AND ANALYSIS [PDF]
, 2001 A high performance fan stage of pressure ratio 2.0 is being designed and developed under a joint programme between Chinese Aeronautical Establishment (CAE) China and National Aerospace Laboratories (NAL), Bangalore, India..
Anantha Murhy, MV +5 more
core
Downregulation of microRNA-512-3p enhances the viability and suppresses the apoptosis of vascular endothelial cells, alleviates autophagy and endoplasmic reticulum stress as well as represses atherosclerotic lesions in atherosclerosis by adjusting spliced/unspliced ratio of X-box binding protein 1 (XBP-1S/XBP-1U) [PDF]
, 2021 Peipei Ge +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Tensile and compressive test results for metal matrix composites [PDF]
Experimental results of the mechanical behavior of two metal matrix composite systems at room temperature are presented. Ultimate stress, ultimate strain, Poisson's ratio, and initial Young's Modulus are documented for BORSIC/Aluminum in uniaxial tension
Herakovich, C. T., Shuart, M. J.
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Clinical Interventions in Aging, 2021 Chengxiang Yuan,1,* Siyan Chen,1,* Yiting Ruan,1 Yuntao Liu,1 Haoran Cheng,1 Yaying Zeng,1 Yunbin Chen,1 Qianqian Cheng,2 Guiqian Huang,1 Weilei He,1 Jincai He1 1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University ...
Yuan C +10 more
doaj
Stress state at faults: the influence of rock stiffness contrast, stress orientation, and ratio [PDF]
Solid EarthThe contemporary crustal stress state is primarily driven by gravitational volume forces and plate tectonics. However, there are various smaller-scale sources such as geological structures and stiffness contrast that perturb stresses and deviate them ...
M. O. Ziegler +10 more
doaj +1 more source
Stress and Strain in Flat Piling of Disks
, 2003 We have created a flat piling of disks in a numerical experiment using the Distinct Element Method (DEM) by depositing them under gravity. In the resulting pile, we then measured increments in stress and strain that were associated with a small decrease ...
Arthur J. R. F. +17 more
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source