Results 111 to 120 of about 3,048,656 (303)

The Stress Hyperglycemia Ratio is Associated with Hemorrhagic Transformation in Patients with Acute Ischemic Stroke

open access: yesClinical Interventions in Aging, 2021
Chengxiang Yuan,1,* Siyan Chen,1,* Yiting Ruan,1 Yuntao Liu,1 Haoran Cheng,1 Yaying Zeng,1 Yunbin Chen,1 Qianqian Cheng,2 Guiqian Huang,1 Weilei He,1 Jincai He1 1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University ...
Yuan C   +10 more
doaj  

The effect of thickness on fatigue crack propagation in 7475-T731 aluminum alloy sheet [PDF]

open access: yes
Tests were conducted on three thicknesses of 7475-T731 aluminum alloy sheet to investigate the effect of thickness on fatigue crack propagation under constant amplitude loading conditions and on retardation following a single peak overload.
Daiuto, R. A., Hillberry, B. M.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Critical Thickness Ratio for Buckled and Wrinkled Fruits and Vegetables

open access: yes, 2013
Fruits and vegetables are usually composed of exocarp and sarcocarp and they take a variety of shapes when they are ripe. Buckled and wrinkled fruits and vegetables are often observed. This work aims at establishing the geometrical constraint for buckled
Dai, Hui-Hui, Liu, Yang
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A study of fatigue crack closure using electric potential and compliance techniques [PDF]

open access: yes
Compared are closure data produced on the same specimen by the crack tip compliance gage and electric potential techniques. Experiments on 7075-T651 aluminum center cracked panels produced equivalent results on closure using the two techniques.
Cassatt, G. C., Clarke, C. K.
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Effects of Stress Ratio and Stress Wave Frequency on Rock Crack Propagation and Damage Evolution during Rockburst

open access: yesJournal of Applied Science and Engineering
Rockburst is a dynamic instability phenomenon in deep underground engineering, fundamentally governed by crack initiation, propagation, and rapid energy release in highly stressed brittle rock masses.
Deng Xianshi   +4 more
doaj   +1 more source

Technical SWOT analysis of decentralised production for low voltage grids in Flanders [PDF]

open access: yes, 2012
The increasing energy prices, combined with high funding by the government, has resulted in a massive integration of decentralised electrical energy production units in Belgium.
Debruyne, Colin   +3 more
core  

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