Results 71 to 80 of about 2,387,231 (339)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Interlukin-4 weakens resistance to stress injury and megakaryocytic differentiation of hematopoietic stem cells by inhibiting Psmd13 expression [PDF]

, 2023
Ai Gao, Xu ShuHui, Qing Li, Caiying Zhu, Fengjiao Wang, Yajie Wang, Sha Hao, Fang Dong, Hui Cheng, Tao Cheng, Yuemin Gong   +10 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Identification of nuclear membrane SUN proteins and components associated with wheat fungal stress responses

Stress Biology
In eukaryotes, the nuclear membrane that encapsulates genomic DNA is composed of an inner nuclear membrane (INM), an outer nuclear membrane (ONM), and a perinuclear space.
Huan Guo, Jianfeng Wang, Di Yao, Ligang Yu, Wenting Jiang, Lincai Xie, Shikai Lv, Xiangyu Zhang, Yajuan Wang, Changyou Wang, Wanquan Ji, Hong Zhang   +11 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

OsSCYL2 is Involved in Regulating ABA Signaling-Mediated Seed Germination in Rice

Plants
Seed germination represents a multifaceted biological process influenced by various intrinsic and extrinsic factors. In the present study, our investigation unveiled the regulatory role of OsSCYL2, a gene identified as a facilitator of seed germination ...
Minyan Xu, Wei Zhang, Yuhuan Jiao, Qing Yang, Meng Chen, Hu Cheng, Beijiu Cheng, Xin Zhang   +7 more
doaj   +1 more source

New Wolbachia pipientis Genotype Increasing Heat Stress Resistance of Drosophila melanogaster Host Is Characterized by a Large Chromosomal Inversion [PDF]

, 2022
Aleksandra Korenskaia, Olga D. Shishkina, Alexandra I. Klimenko, Olga V. Andreenkova, Мargarita А. Bobrovskikh, Natalja V. Shatskaya, Gennady V. Vasiliev, Н. Е. Грунтенко   +7 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Identification of the ZmATG18 subfamily genes in maize and the role of ZmATG18a in drought stress

BMC Genomics
Background Autophagy represents an ancient cytoprotective program that sustains cell viability under metabolic or environmental stresses via targeted recycling of cellular components. However, the contribution of ATG18s in maize is ambiguous.
Ziming Wang, Feiyan Luo, Cheng Meng, Jihao Si, Wenzhi Zhang, Jiahao Sun, Zhe Wang   +6 more
doaj   +1 more source

On giant piezoresistance effects in silicon nanowires and microwires

, 2010
The giant piezoresistance (PZR) previously reported in silicon nanowires is experimentally investigated in a large number of surface depleted silicon nano- and micro-structures.
Arscott, S., Milne, J. S., Renner, C., Rowe, A. C. H.   +3 more
core   +4 more sources