Results 41 to 50 of about 4,906,635 (333)
Crosstalk Between ER Stress, Autophagy and Inflammation
The endoplasmic reticulum (ER) is not only responsible for protein synthesis and folding but also plays a critical role in sensing cellular stress and maintaining cellular homeostasis.
Sandhya Chipurupalli +2 more
doaj +1 more source
Effects of osmotic and matric potential on radial growth and accumulation of endogenous reserves in three isolates of Pochonia chlamydosporia [PDF]
For the first time, the effects of varying osmotic and matric potential on fungal radial growth and accumulation of polyols were studied in three isolates of Pochonia chlamydosporia.
Esteves, Ivania +4 more
core +1 more source
Staphylococcus aureus infections are difficult to treat in chronic wounds due to biofilm formation and are frequently compounded by antibiotic resistance, necessitating the development of alternative therapeutic approaches.
Rachel Allen +8 more
doaj +1 more source
Background Root-knot nematodes (RKN) are among the most important root-damaging plant-parasitic nematodes, causing severe crop losses worldwide. The plant rhizosphere and root endosphere contain rich and diverse bacterial communities.
Ye Li +14 more
doaj +1 more source
Interplay between pleiotropy and secondary selection determines rise and fall of mutators in stress response [PDF]
Dramatic rise of mutators has been found to accompany adaptation of bacteria in response to many kinds of stress. Two views on the evolutionary origin of this phenomenon emerged: the pleiotropic hypothesis positing that it is a byproduct of environmental
A Giraud +57 more
core +5 more sources
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga +56 more
wiley +1 more source
Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology
Reactive oxygen species (ROS) are byproducts of aerobic respiration and signaling molecules that control various cellular functions. Nrf2 governs the gene expression of endogenous antioxidant synthesis and ROS-eliminating enzymes in response to various ...
Shuya Kasai +4 more
doaj +1 more source
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard +8 more
wiley +1 more source
The emerging role and therapeutic implications of bacterial and parasitic deubiquitinating enzymes
Deubiquitinating enzymes (DUBs) are emerging as key factors for the infection of human cells by pathogens such as bacteria and parasites. In this review, we discuss the most recent studies on the role of deubiquitinase activity in exploiting and ...
Markus Wehrmann +5 more
doaj +1 more source
Orthotropic cyclic stress-softening model for pure shear during repeated loading and unloading [PDF]
We derive an orthotropic model to describe the cyclic stress softening of a carbon-filled rubber vulcanizate through multiple stress-strain cycles with increasing values of the maximum strain. We specialize the deformation to pure shear loading.
Rickaby, Stephen R., Scott, Nigel H.
core +1 more source

