Results 81 to 90 of about 13,819 (212)

The Impact of Gold, Silver, and Bitcoin Volatility on Banking Systemic Risk: Safe-Haven or Amplifier?

open access: yesRisks
This study examines the dynamic interactions between precious metals (gold and silver) and cryptocurrencies (Bitcoin) in the context of banking systemic risk, by identifying the main banking factors of systemic vulnerability.
Mohamed Amin Chakroun, Faten Abidli
doaj   +1 more source

Clinical Outcomes After Cardiac Stress Testing Among US Patients Younger Than 65 Years

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundScientific statements have championed the measurement of clinical outcomes after cardiac stress testing to better define their value. Using contemporary national data, we sought to describe the characteristics of patients who experience ...
Vinay Kini   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

THE EVOLUTION OF CLIMATE RISK INSURANCE: STRATEGIES FOR INCREASING RESILIENCE IN A CHANGING ENVIRONMENT

open access: yesEconomics & Education
The purpose of the article is to systematize and analytically summarize the transformation of the insurance sector under the influence of climate risks and identify mechanisms for increasing its financial stability in the face of increasing catastrophic
Kateryna Zdor
doaj   +1 more source

Overnight Index Rate: Model, calibration and simulation

open access: yesCogent Economics & Finance, 2014
In this study, the extended Overnight Index Rate (OIR) model is presented. The fitting function for the probability distribution of the OIR daily returns is based on three different Gaussian distributions which provide modelling of the narrow central ...
Olga Yashkir, Yuri Yashkir
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Improving Credit Risk Assessment in Uncertain Times: Insights from IFRS 9

open access: yesRisks
This study highlights the superior performance of Bayesian Model Averaging (BMA) in credit risk modeling under IFRS 9, particularly during economic uncertainty, such as the COVID-19 pandemic. Using granular bank-level data from Malta, spanning 2017–2023,
Petr Jakubik, Saida Teleu
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

After ischemia trial, what is the role of ischemia detection on noninvasive testing?

open access: yesHeart Views, 2020
Abdul Rahman Arabi   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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