Results 101 to 110 of about 905,110 (306)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

TO THE QUESTION ABOUT THE INFLUENCE OF THE STRESSES IN THE ELEMENTS OF THE REINFORCEMENT SHAFTS AT THE RATE OF CORROSION

Nauka ta progres transportu, 2008
On the basis of laboratory explorations the features of conducting the corrosive process in the shaft reinforcement parts under the load from lifting buckets and rock mass were determined.
V. V. Kovalenko, I. V. Kupenko, O. Yu. Prokopov, S. V. Karhapolov   +3 more
doaj  

Tectonic-structural systems of Mars: Is it possible to use them to reconstruct its thermal evolution? [PDF]

Geofísica Internacional, 2004
This work tries to establish the possible relationship among cortical stresses evidenced by faults mapped in the surface and thermal evolution on Mars.
J. F. Valdés-Galicia, Antonio H. Barosio   +1 more
doaj  

Closed system of coupling effects in generalized thermo-elastoplasticity

International Journal of Applied Mechanics and Engineering, 2016
In this paper, the field equations of the generalized coupled thermoplasticity theory are derived using the postulates of classical thermodynamics of irreversible processses. Using the Legendre transformations two new thermodynamics potentials P and S
Z. Śloderbach
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Residual stresses and deformations in a welded thin-walled pipe

, 1989
Deformations and stresses during butt-welding of a pipe are calculated as well as the residual deformations and stresses. The temperature field during welding is calculated using an analytical solution. The deformations and stresses are calculated by use
Näsström, Mats,, Jonsson, Mikael, Lindgren, Lars-Erik,, Karlsson, Lennart,, Trovie, L.   +4 more
core  

An experimental and computational investigation of bone cement residual stresses [PDF]

, 2006
Hip arthroplasty is a common orthopaedic procedure with considerable success in alleviating hip joint pain and disability. To transfer loads from the prosthesis to the contiguous bone, self-curing polymethyl methacrylate, often referred to as bone cement,
Hingston, John A.
core   +2 more sources

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source