Results 111 to 120 of about 747,930 (316)

Tectonic-structural systems of Mars: Is it possible to use them to reconstruct its thermal evolution? [PDF]

open access: yesGeofísica Internacional, 2004
This work tries to establish the possible relationship among cortical stresses evidenced by faults mapped in the surface and thermal evolution on Mars.
J. F. Valdés-Galicia   +1 more
doaj  

Closed system of coupling effects in generalized thermo-elastoplasticity

open access: yesInternational Journal of Applied Mechanics and Engineering, 2016
In this paper, the field equations of the generalized coupled thermoplasticity theory are derived using the postulates of classical thermodynamics of irreversible processses. Using the Legendre transformations two new thermodynamics potentials P and S
Z. Śloderbach
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Simple formulas for thermoelastic stresses in TBC coatings

open access: yes, 2003
Thin coatings on metallic substrates are extensively used in mechanical, aerospace, microelectronic, optical, and medical applications. Coatings affect the surface properties of the system, while bulk properties and strength primarily depend on the ...
Tagarelli, V.L.   +3 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

3D Residual Stresses in Selective Laser Melted Hastelloy X

open access: yes, 2017
3D residual stresses in as manufactured EOS NickelAlloy HX, produced by laser powder bed additive manufacturing, are analysed on the surface closest to the build-plate.
Saarimäki, Jonas,   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Synchrotron strain scanning for residual stress measurement in cold-drawn steel rods

open access: yes, 2011
Cold-drawn steel rods and wires retain significant residual stresses as a consequence of the manufacturing process. These residual stresses are known to be detrimental for the mechanical properties of the wires and their durability in aggressive ...
M Elices   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Stress [PDF]

open access: yesActa Physiologica, 2016
P B, Persson, A, Zakrisson
openaire   +2 more sources

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