Results 101 to 110 of about 4,593,130 (335)

The long-term effects of consecutive COVID-19 waves on mental health

BJPsych Open
Background Although several studies have documented the impact of the COVID-19 pandemic on mental health, the long-term effects remain unclear. Aims To examine longitudinal changes in mental health before and during the consecutive COVID-19 waves in a ...
Jan Sebastian Novotný, Juan Pablo Gonzalez-Rivas, Šárka Kunzová, Mária Skladaná, Anna Pospíšilová, Anna Polcrová, Maria Vassilaki, Jose Ramon Medina-Inojosa, Francisco Lopez-Jimenez, Yonas Endale Geda, Gorazd Bernard Stokin   +10 more
doaj   +1 more source

Effects of stress on the immune system of fish [PDF]

, 1994
The effects of stress on the immune system of various fish species including dab Limanda limanda, flounder Platichthys flesus, sea bass Dicentrarchus labrax and gobies Zosterisessor ophiocephalus, were investigated from laboratory and field experiments ...
Farley, S., Lemaire-Gony, S., Pulsford, A.L.   +2 more
core  

Ontogeny influences sensitivity to climate change stressors in an endangered fish. [PDF]

, 2014
Coastal ecosystems are among the most human-impacted habitats globally, and their management is often critically linked to recovery of declining native species.
Castillo, G, Cheng, BS, Connon, RE, Fangue, NA, Hasenbein, M, Komoroske, LM, Lindberg, J   +6 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

More than a feeling: A unified view of stress measurement for population science. [PDF]

, 2018
Stress can influence health throughout the lifespan, yet there is little agreement about what types and aspects of stress matter most for human health and disease.
Crosswell, Alexandra D, Epel, Elissa S, Mayer, Stefanie E, Mendes, Wendy Berry, Prather, Aric A, Puterman, Eli, Slavich, George M   +6 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The attachment system and physiology in adulthood: normative processes, individual differences, and implications for health. [PDF]

, 2014
Attachment theory provides a conceptual framework for understanding intersections between personality and close relationships in adulthood. Moreover, attachment has implications for stress-related physiology and physical health.
Ainsworth, Avitsur, Baumeister, Beedie, Biomarker Definitions Working Group, Bolger, Bowlby, Bowlby, Bowlby, Brennan, Brooks, Bullmore, Carmichael, Coan, Coan, Collins, Collins, Collins, Collins, Dallman, DeVries, DeWall, Diamond, Diamond, Diamond, Diamond, Dickerson, Eisenberger, Epel, Fraley, Fraley, Gailliot, Gouin, Hagger, Hasler, Hazan, Hazan, Hicks, Hofer, Holland, Holt-Lunstad, Kane, Kidd, Kiecolt-Glaser, Kiecolt-Glaser, Kiecolt-Glaser, Kirschbaum, Kurzban, Laurenceau, Lovallo, Master, Maunder, Maunder, McClure, McEwen, McWilliams, Mikulincer, Miller, Molden, Pasch, Peters, Pietromonaco, Polan, Powers, Quirin, Ridker, Roberts, Robles, Robles, Robles, Roisman, Salvy, Sanders, Sapolsky, Sbarra, Scharfe, Souza, Stumvoll, Taylor, Troxel, Troxel, Troxel, Troxel, Uchino, Vaishnavi, Vormbrock, Vrtička, Vrtička, Walburn   +88 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Preventing a Risk/Risk Trade-off: An Analysis of the Measures Necessary to Increase U.S. Pollinator Numbers [PDF]

, 2017
This Note will proceed in four parts. Part II will discuss the importance of pollinators and the possible reasons for their declining numbers. Part III will delve into the current and proposed actions to increase pollinator populations that are taking ...
Acchiardo Vallejo, Camila
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source