Results 221 to 230 of about 325,395 (379)

Neuronal α‐Synuclein Disease Stage Progression over 5 Years

open access: yesMovement Disorders, EarlyView.
Abstract Background Neuronal α‐synuclein disease (NSD) is defined by the presence of an in vivo biomarker of neuronal alpha‐synuclein (n‐asyn) pathology. The NSD integrated staging system (NSD‐ISS) for research describes progression across the disease continuum as stages 0 to 6.
Tanya Simuni   +205 more
wiley   +1 more source

Neuropathological and Behavioral Consequences of Adeno-Associated Viral Vector-Mediated Continuous Intrastriatal Neurotrophin Delivery in a Focal Ischemia Model in Rats

open access: yesNeurobiology of Disease, 2002
Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) were continuously delivered to the striatum at biologically active levels via recombinant adeno-associated viral (rAAV) gene transfer 4–5 weeks prior to 30 min of middle cerebral ...
Gunnar Andsberg   +5 more
doaj  

Intraputaminal Delivery of Adeno‐Associated Virus Serotype 2–Glial Cell Line–Derived Neurotrophic Factor in Mild or Moderate Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Glial cell line–derived neurotrophic factor (GDNF) is required for development and survival of dopaminergic neurons. A previous trial evaluating lower‐dose adeno‐associated virus serotype 2–GDNF (AAV2‐GDNF) bilateral intraputaminal infusion in participants with advanced Parkinson's disease (PD) achieved 26% mean putaminal coverage ...
Amber D. Van Laar   +10 more
wiley   +1 more source

Estrogen and memory system bias in females across the lifespan

open access: yesTranslational Neuroscience, 2014
Hussain Dema, Shams Waqqas, Brake Wayne
doaj   +1 more source

Genes That Associated with Action of ACTH-like Peptides with Neuroprotective Potential in Rat Brain Regions with Different Degrees of Ischemic Damage. [PDF]

open access: yesInt J Mol Sci
Filippenkov IB   +11 more
europepmc   +1 more source

Arkypallidal Cells Send a Stop Signal to Striatum

open access: yesNeuron, 2016
N. Mallet   +6 more
semanticscholar   +1 more source

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou   +6 more
wiley   +1 more source

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