Results 241 to 250 of about 325,395 (379)
Shifted Balance Between Ventral Striatal Prodynorphin and Proenkephalin Biases Development of Cocaine Place Avoidance. [PDF]
Nicot A+4 more
europepmc +1 more source
A Scalable Population Code for Time in the Striatum
Gustavo B. M. Mello+2 more
semanticscholar +1 more source
Abstract Background Breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in basal ganglia cells through hydrolysis of diesteric bonds, primarily by PDE10A and PDE1B, is essential for normal human movement. While biallelic loss‐of‐function variants in PDE10A are known to cause hyperkinetic movement disorders, the ...
Tomer Poleg+21 more
wiley +1 more source
Whole-Brain Confocal Imaging Provides an Accurate Global View of the Nigral Dopamine System. [PDF]
Zhou FM.
europepmc +1 more source
A Convergent Pathway for Stimulation‐Induced Dyskinesia Following Deep Brain Stimulation
Abstract Background Stimulation‐induced dyskinesias (SID) from deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus pallidus internus (GPi) are uncommon; however, they are increasingly recognized. Once considered transient and indicative of effective neuromodulation, SID are now seen as potential therapy‐limiting side effects, akin ...
Joshua K. Wong+4 more
wiley +1 more source
Hemichorea Associated With Nigrostriatal Dysfunction: Case Report of a Patient With an Ipsilateral Infarct in the Lenticular Nucleus and Internal Capsule. [PDF]
Kobayashi M.
europepmc +1 more source
Striatal cue-reactivity and neurotransmitter function in gambling disorder. [PDF]
Bellmunt-Gil A+7 more
europepmc +1 more source
Abstract Traditionally, clinical trials of putative disease‐modifying therapies in Parkinson's disease have enrolled untreated patients at the earliest clinical stages of their disease. Due to a number of challenges inherent with this approach, there has been a recent move to a different study design, enrolling patients who are already taking “stable ...
M. Maral Mouradian+2 more
wiley +1 more source