Results 101 to 110 of about 95,064 (284)

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

The complex Liouville string: Worldsheet boundaries and non-perturbative effects

open access: yesSciPost Physics
We investigate general observables of the complex Liouville string with worldsheet boundaries. We develop a universal formalism that reduces such observables to ordinary closed string amplitudes without boundaries, applicable to any worldsheet string ...
Scott Collier, Lorenz Eberhardt, Beatrix Mühlmann, Victor A. Rodriguez
doaj   +1 more source

O(D, D) gauge fields in the T-dual string Lagrangian

open access: yesJournal of High Energy Physics, 2019
We present the string Lagrangian with manifest T-duality. Not only zero-modes but also all string modes are doubled. The gravitational field is an O(D, D) gauge field.
Machiko Hatsuda, Warren Siegel
doaj   +1 more source

String duality and modular forms [PDF]

open access: yesPhysics Letters B, 1997
Tests of duality between heterotic strings on $K3\times T^2$ (restricted on certain Narain moduli subspaces) and type IIA strings on K3-fibered Calabi-Yau threefolds are attempted in the weak coupling regime on the heterotic side by identifying pertinent modular forms related to the computations of string threshold corrections. Concretely we discuss in
openaire   +2 more sources

String breaking, baryons, medium, and gauge/string duality [PDF]

open access: yesPhysical Review D, 2020
20 pages, 7 figures, extended version of arXiv:1909.12771; v2: minor corrections; v3: matches published ...
openaire   +2 more sources

T-duality in arbitrary string backgrounds [PDF]

open access: yesNuclear Physics B, 1996
T-Duality is a poorly understood symmetry of the space-time fields of string theory that interchanges long and short distances. It is best understood in the context of toroidal compactification where, loosely speaking, radii of the torus are inverted.
Evans, Mark, Giannakis, Ioannis
openaire   +2 more sources

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman   +5 more
wiley   +1 more source

Dualities of fields and strings [PDF]

open access: yesStudies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics, 2017
Duality, the equivalence between seemingly distinct quantum systems, is a curious property that has been known for at least three quarters of a century. In the past two decades it has played a central role in mapping out the structure of theoretical physics.
openaire   +3 more sources

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

open access: yesAdvanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy