Results 101 to 110 of about 257,053 (199)
A microscopic realization of dS$_3$
SciPost PhysicsWe propose a precise duality between pure de Sitter quantum gravity in $2+1$ dimensions and a double-scaled matrix integral. This duality unfolds in two distinct aspects.
Scott Collier, Lorenz Eberhardt, Beatrix Mühlmann
doaj +1 more source
Thermal duality and gravitational collapse in heterotic string theories
, 2013 The thermal duality of E(8)$ x $E(8) and SO(32) heterotic string theories may underpin a mechanism that would convert the kinetic energy of infalling matter during gravitational collapse to form a region of a hot string phase that would expel ...
Hewitt, M.
core
An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Advanced Science, EarlyView.Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source
Locality and causality properties of light cone string field theory [PDF]
, 2004 The recent discovery of a new maximally supersymmetric background for the type IIB superstring theory has revived the interest in light cone string field theory.
Kyritisis, Konstantinos
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Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution
Advanced Science, EarlyView.MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge +6 more
wiley +1 more source
The spatial Wilson loops, string breaking, and AdS/QCD
Physics Letters BWe consider the phenomenon of string breaking in the context of the spatial Wilson loops using the gauge/string duality. In particular, we discuss the impact of light flavors on the pseudopotential.
Oleg Andreev
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The simplest gauge-string duality [PDF]
, 2015 A dissertation submitted to the University of the Witwatersrand, Faculty of Science in ful lment of the academic requirements of the degree of Master of Science. Johannesburg, 2015.The gauge/gravity correspondence is a conjectured exact duality between
Nkumane, Lwazi Khethukuthula
core
Advanced Science, EarlyView.Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken +8 more
wiley +1 more source
Advanced Science, EarlyView.ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu +12 more
wiley +1 more source
SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer
Advanced Science, EarlyView.Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian +8 more
wiley +1 more source