Results 111 to 120 of about 475,776 (345)

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

Advanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino, Phuoc Thien Phan, James Davies, Bibhu Sharma, Tianruo Guo, Chi Cong Nguyen, Nigel H. Lovell, Thanh Nho Do   +7 more
wiley   +1 more source

Open String Field Theory around Universal Solutions

, 2002
We study the physical spectrum of cubic open string field theory around universal solutions, which are constructed using the matter Virasoro operators and the ghost and anti-ghost fields. We find the cohomology of the new BRS charge around the solutions,
Frenkel, I. Kishimoto, T. Takahashi
core   +1 more source

Fundamental string solutions in open string field theories [PDF]

Physical Review D, 2006
In Witten's open cubic bosonic string field theory and Berkovits' superstring field theory we investigate solutions of the equations of motion with appropriate source terms, which correspond to Callan-Maldacena solution in Born-Infeld theory representing fundamental strings ending on the D-branes.
openaire   +2 more sources

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Wilsonian effective potentials and closed string field theory

Journal of High Energy Physics
We investigate Wilsonian effective field theory as a model for the construction of the tachyon potential and nonperturbative vacua in closed string field theory.
Theodore Erler, Atakan Hilmi Fırat
doaj   +1 more source

Open string stub as an auxiliary string field

SciPost Physics
Witten's open string field theory with a generalized version of stubs is reformulated as a cubic string field theory using an auxiliary string field. The gauge symmetries and equations of motion as well as the associative algebra of the resulting theory ...
Harold Erbin, Atakan Hilmi Firat
doaj   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Adding stubs to quantum string field theories

Journal of High Energy Physics
Generalizing recent work by Schnabl-Stettinger and Erbin-Fırat, we outline a universal algebraic procedure for ‘adding stubs’ to string field theories obeying the BV quantum master equation.
C. Maccaferri, R. Poletti, A. Ruffino, B. Valsesia   +3 more
doaj   +1 more source

The bosonic string on string-size tori from double field theory

Journal of High Energy Physics, 2017
We construct the effective action for toroidal compactifications of bosonic string theory from generalized Scherk-Schwarz reductions of double field theory.
Yago Cagnacci, Mariana Graña, Sergio Iguri, Carmen Nuñez   +3 more
doaj   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source