Results 131 to 140 of about 458,083 (347)

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

open access: yesAdvanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li   +11 more
wiley   +1 more source

String field theory

open access: yesNuclear Physics B, 1986
A gauge invariant field theory of the bosonic string is formulated following Siegel, Banks and Peskin, and Feigin and Fuks. The free field action is constructed from the Virasoro operators assuming only locality. The propagator is very regular at short distance.
openaire   +2 more sources

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang   +6 more
wiley   +1 more source

The T-dual symmetries of a bosonic string

open access: yesEuropean Physical Journal C: Particles and Fields, 2018
We investigate whether the symmetry transformations of a bosonic string are connected by T-duality. We start with a standard closed string theory. We continue with a modified open string theory, modified to preserve the symmetry transformations possessed
Ljubica Davidović, Branislav Sazdović
doaj   +1 more source

Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T‐Cell Function and Anti‐PD‐1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T‐Cell‐Incorporated Tumor Organoid Studies

open access: yesAdvanced Science, EarlyView.
Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren   +7 more
wiley   +1 more source

Novel string field theory with also negative energy constituents/objects gives Veneziano amplitude

open access: yesJournal of High Energy Physics, 2018
We have proposed a new type of string field theory. The main point of the present article is to cure some technical troubles: missing two out three terms in Veneziano amplitude. Our novel string field theory, describes a theory with many strings in terms
H.B. Nielsen, M. Ninomiya
doaj   +1 more source

An Exact Bosonization Rule for c=1 Noncritical String Theory

open access: yes, 2007
We construct a string field theory for c=1 noncritical strings using the loop variables as the string field. We show how one can express the nonrelativistic free fermions which describes the theory, in terms of these string fields.Comment: 17 pages, to ...
A. Dhar   +14 more
core   +2 more sources

Observation of Magnetic Pseudogap Behavior in Phosphorus‐Doped Silicon

open access: yesAdvanced Science, EarlyView.
Phosphorus‐doped silicon presents a promising platform for quantum computing and hosts a Kondo condensate state featuring a pseudogap. Thermodynamic and magnetic resonance measurements reveal that this pseudogap behavior involves critical spin fluctuations, suggesting that overlapping Kondo clouds form a correlated coherent magnetic ground state ...
Suheon Lee   +16 more
wiley   +1 more source

Deformation of the cubic open string field theory

open access: yesPhysics Letters B, 2017
We study a consistent deformation of the cubic open bosonic string theory in such a way that the non-planar world sheet diagrams of the perturbative string theory are mapped onto their equivalent planar diagrams of the light-cone string field theory with
Taejin Lee
doaj   +1 more source

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