Results 91 to 100 of about 30,797 (247)

Genetic Etiologies of Dystonia with Anarthria/Aphonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dystonia with anarthria and/or aphonia (DAnAp) represents a distinctive phenotype manifesting across lifespan. Frequently associated with genetic disorders, early recognition is critical for diagnosis and management. Objectives To provide practical recommendations for the clinical evaluation of patients with DAnAp, enhancing ...
Anika Ménétrey, Eriberto Rayco, Maziar Emamikhah Abarghouei, Susan H. Fox, Anthony E. Lang, George M. Ibrahim, Carolina Gorodetsky, Christos Ganos   +7 more
wiley   +1 more source

Optimising therapeutic strategies for acute stroke-like lesions in MELAS

eNeurologicalSci, 2020
Josef Finsterer
doaj   +1 more source

Elderly onset of MELAS carried an M.3243A >G mutation in a female with deafness and visual deficits: A case report

Clinical Case Reports
Key Clinical Message MELAS is a disorder with clinical variability that also responsible for a significant portion of unexplained hereditary or childhood‐onset hearing loss.
Lin Zijun, Yi Xu, Yang Yujia, Xu Zhiqiang   +3 more
doaj   +1 more source

Mitochondrial Complex I Deficiency Masquerading as Stroke-Like Episode Clinically and as Alexander Disease Radiologically Following Chicken Pox. [PDF]

Ann Indian Acad Neurol, 2023
Gowda VK, Bylappa AY, Kinhal U, Srinivasan VM, Vamyanmane DK.   +4 more
europepmc   +1 more source

A Gap Analysis of Deep Brain Stimulation for Childhood‐Onset Movement Disorders

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established and increasingly utilized therapy for childhood‐onset movement disorders. However, pediatric DBS poses unique challenges that are not adequately addressed by adult‐derived paradigms. Objective To identify key gaps in the current use of DBS in childhood‐onset movement disorders and to ...
Daniela Munoz‐Chesta, Carolina Gorodetsky, Todd M. Herrington, Angela L. Hewitt, Daniel E. Lumsden, Jennifer O'Malley, Terence Sanger   +6 more
wiley   +1 more source

Ursodeoxycholic Acid and Parkinson's Disease Risk: An Emulated Target Trial in UK Electronic Health Records

Movement Disorders, EarlyView.
Abstract Background Ursodeoxycholic acid (UDCA) has shown mitochondrial and neuroprotective effects and has been proposed as a treatment for Parkinson's disease (PD). However, population‐level evidence on its effect on PD risk is lacking. Objectives To compare the risk of incident PD among UDCA initiators versus matched non‐initiators within a ...
Chengsheng Ju, Anette Schrag, Camille Carroll, Xi Xiong, James Carpenter, Oliver Bandmann, Thomas Foltynie, Li Wei   +7 more
wiley   +1 more source

Determinants of Cueing Responsiveness in Parkinson's Disease: Insights from the UNITE‐PD Study

Movement Disorders, EarlyView.
Abstract Background Cueing strategies are widely used to improve gait in Parkinson's disease (PD), but interindividual variability in cueing responsiveness remains poorly understood. Objectives The objective of the study was to identify determinants of internal and external cueing efficacy in persons with PD.
Cindel Albers, Laura Avanzino, Elsa de Lange, Alessandro Botta, Zoya Katzir, Matan Bouter, Veronica Romano, Moran Gilat, Bastiaan R. Bloem, Joris van der Cruijsen, Inbal Maidan, Alice Nieuwboer, Elisa Pelosin, Anouk Tosserams, Vivian Weerdesteyn, Anat Mirelman, Jorik Nonnekes   +16 more
wiley   +1 more source

Learning curve of nurse‐performed electromagnetic‐guided nasogastric tube placement in adult ICU patients: A multicenter prospective study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Safe and timely nasogastric tube (NGT) placement is essential for effective enteral nutrition delivery in critically ill patients. Electromagnetic‐guided systems has been shown to improve placement accuracy and may reduce delays from confirmatory imaging, but evidence on how nurses acquire competence with this technology remains ...
Kazunao Mori, Hideaki Sakuramoto, Tomoaki Ikezawa, Megumi Kamogawa, Hideaki Note, Toshifumi Miki, Saiko Okamoto, Maiko Motoki, Hideki Hashimoto, Junko Tatsuno, Tomomi Yoshida, Saori Kajiwara, Masako Shirasaka, Megumi Mukouyama, Hitoshi Tsugu, Kensuke Nakamura   +15 more
wiley   +1 more source

Cardiopulmonary Exercise Testing (CPET) Guided Sub‐Anaerobic Threshold Rehabilitation in MELAS Syndrome: A Case Report

The Kaohsiung Journal of Medical Sciences, EarlyView.
Yu‐Lien Tsai, Kun‐Yuan Cheng, Yen‐Sen Lu, Ko‐Long Lin   +3 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source