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Heat stroke-like episode in a child caused by zonisamide

Brain and Development, 1997
A 2-year-old mentally retarded boy with frontal lobe epilepsy presented with an episode that resembled heat stroke during the administration of zonisamide. He developed hyperpyrexia with oligohidrosis and central neurological symptoms, including, chorea-like involuntary movements, resting tremor, and cogwheel rigidity.
T Matsuishi, Akio Ohnishi
exaly   +3 more sources

Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes diagnosed after metformin-triggered stroke-like episodes

Journal of Stroke and Cerebrovascular Diseases, 2023
A 40-year-old man with sensorineural hearing loss and diabetes mellitus was hospitalized with acute-onset impaired consciousness and clumsiness in his left hand. He had been taking metformin for 4 months. A neurological examination revealed confusion and weakness in the left upper limb.
Keishu Murakami   +3 more
openaire   +2 more sources

Reply: Stroke-like episode of the optic nerve

Canadian Journal of Ophthalmology
Heather Mack   +2 more
exaly   +3 more sources

Neuroimaging of stroke-like episodes in MELAS

Brain and Development, 2011
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) shows sudden neurological deficits that are called 'stroke-like episodes'. With regard to the pathophysiology of stroke-like episodes, so-called mitochondrial angiopathy and cytopathy theories have been proposed, but the subject is still controversial.
Hiromichi, Ito   +2 more
openaire   +2 more sources

Stroke-like episodes, peri-episodic seizures, and MELAS mutations

European Journal of Paediatric Neurology, 2016
Stroke-like episodes (SLEs) are a hallmark of various mitochondrial disorders, in particular MELAS syndrome. SLEs manifest with vasogenic oedema (DWI and ADC hyperintensity) or partial cytotoxic oedema (DWI hyperintensity, ADC hypointensity) in the acute and subacute stage, and with gyriform T1-hyperintensity (cortical necrosis) in the chronic stage ...
Josef, Finsterer, Salma Majid, Wakil
openaire   +2 more sources

Management of mitochondrial stroke‐like‐episodes

European Journal of Neurology, 2009
Aim of this review is to discuss recent findings concerning the management of stroke‐like episodes (SLEs) in patients with mitochondrial disorders (MIDs). Various databases were searched for appropriate literature. SLEs are a dominant feature of MIDs and occur most frequently in MELAS‐syndrome, less frequently in MERRF‐syndrome, Kearns‐Sayre‐syndrome ...
openaire   +2 more sources

Stroke-Like Episodes in Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS)

2012
The syndrome of mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is a disease marked by a clinical triad of (1) stroke-like episode (SLE) before age 40 years, (2) encephalopathy characterized by seizures and dementia, and (3) lactic acidosis and ragged red fibers.
Douglas M. Sproule   +3 more
openaire   +1 more source

Platelet function in mitochondriopathy with stroke and stroke-like episodes

Thrombosis and Haemostasis, 2004
SummaryStroke and stroke-like episodes are frequent complications in mitochondriopathy, particulary in MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke like episodes) which is a disorder of the mitochondrial oxidative metabolism in diverse cell types.
Nicole, Kotzailias   +5 more
openaire   +2 more sources

Neuronal hyperexcitability in stroke-like episodes of MELAS syndrome

Neurology, 2002
The pathogenesis of stroke-like episodes in patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) remains unknown.Fourteen stroke-like episodes in six patients with MELAS were studied using clinical, neuroradiologic, and electrophysiologic approaches.
T, Iizuka   +6 more
openaire   +2 more sources

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